Literature DB >> 25436795

Intensity-modulated radiotherapy for lung cancer: current status and future developments.

Clara Chan1, Stephanie Lang, Carl Rowbottom, Matthias Guckenberger, Corinne Faivre-Finn.   

Abstract

Radiotherapy plays an important role in the management of lung cancer, with over 50% of patients receiving this modality at some point during their treatment. Intensity-modulated radiotherapy (IMRT) is a technique that adds fluence modulation to beam shaping, which improves radiotherapy dose conformity around the tumor and spares surrounding normal structures. Treatment with IMRT is becoming more widely available for the treatment of lung cancer, despite the paucity of high level evidence supporting the routine use of this more resource intense and complex technique. In this review article, we have summarized data from planning and clinical studies, discussed challenges in implementing IMRT, and made recommendations on the minimum requirements for safe delivery of IMRT.

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Year:  2014        PMID: 25436795     DOI: 10.1097/JTO.0000000000000346

Source DB:  PubMed          Journal:  J Thorac Oncol        ISSN: 1556-0864            Impact factor:   15.609


  24 in total

1.  Genetic variants in the ITGB6 gene is associated with the risk of radiation pneumonitis in lung cancer patients treated with thoracic radiation therapy.

Authors:  Minxiao Yi; Yang Tang; Bo Liu; Qianxia Li; Xiao Zhou; Shiying Yu; Shengling Fu; Yixin Cai; Xianglin Yuan
Journal:  Tumour Biol       Date:  2015-10-08

2.  Calculating and estimating second cancer risk from breast radiotherapy using Monte Carlo code with internal body scatter for each out-of-field organ.

Authors:  Takeshi Takata; Kenshiro Shiraishi; Shinobu Kumagai; Norikazu Arai; Takenori Kobayashi; Hiroshi Oba; Takahide Okamoto; Jun'ichi Kotoku
Journal:  J Appl Clin Med Phys       Date:  2020-10-30       Impact factor: 2.102

3.  Impact of modern radiotherapy techniques on survival outcomes for unselected patients with large volume non-small cell lung cancer.

Authors:  Raj Kumar Shrimali; Santam Chakraborty; Sriram Prasath; B Arun; Sanjoy Chatterjee
Journal:  Br J Radiol       Date:  2018-11-29       Impact factor: 3.039

Review 4.  Advanced radiation techniques for locally advanced non-small cell lung cancer: intensity-modulated radiation therapy and proton therapy.

Authors:  Nikhil Yegya-Raman; Wei Zou; Ke Nie; Jyoti Malhotra; Salma K Jabbour
Journal:  J Thorac Dis       Date:  2018-08       Impact factor: 2.895

5.  Comparative effectiveness of intensity modulated radiation therapy to 3-dimensional conformal radiation in locally advanced lung cancer: pathological and clinical outcomes.

Authors:  Sarit Appel; Jair Bar; Alon Ben-Nun; Marina Perelman; Dror Alezra; Damien Urban; Maoz Ben-Ayun; Nir Honig; Efrat Ofek; Tamar Katzman; Amir Onn; Sumit Chatterji; Sergey Dubinski; Lev Tsvang; Shira Felder; Judith Kraitman; Ory Haisraely; Tatiana Rabin Alezra; Sivan Lieberman; Edith M Marom; Nir Golan; David Simansky; Zvi Symon; Yaacov Richard Lawrence
Journal:  Br J Radiol       Date:  2019-04-01       Impact factor: 3.039

Review 6.  Thoracic radiotherapy in small cell lung cancer-a narrative review.

Authors:  Antonin Levy; Angela Botticella; Cécile Le Péchoux; Corinne Faivre-Finn
Journal:  Transl Lung Cancer Res       Date:  2021-04

Review 7.  Radiotherapy in the Era of Immunotherapy With a Focus on Non-Small-Cell Lung Cancer: Time to Revisit Ancient Dogmas?

Authors:  Jonathan Khalifa; Julien Mazieres; Carlos Gomez-Roca; Maha Ayyoub; Elizabeth Cohen-Jonathan Moyal
Journal:  Front Oncol       Date:  2021-04-21       Impact factor: 6.244

8.  Protocol for the isotoxic intensity modulated radiotherapy (IMRT) in stage III non-small cell lung cancer (NSCLC): a feasibility study.

Authors:  Kate Haslett; Kevin Franks; Gerard G Hanna; Susan Harden; Matthew Hatton; Stephen Harrow; Fiona McDonald; Linda Ashcroft; Sally Falk; Nicki Groom; Catherine Harris; Paula McCloskey; Philip Whitehurst; Neil Bayman; Corinne Faivre-Finn
Journal:  BMJ Open       Date:  2016-04-15       Impact factor: 2.692

9.  The Response, Outcome and Toxicity of Aggressive Palliative Thoracic Radiotherapy for Metastatic Non-Small Cell Lung Cancer Patients with Controlled Extrathoracic Diseases.

Authors:  Yun Chiang; James Chih-Hsin Yang; Feng-Ming Hsu; Yu-Hsuan Chen; Jin-Yuan Shih; Zhong-Zhe Lin; Keng-Hsueh Lan; Ann-Lii Cheng; Sung-Hsin Kuo
Journal:  PLoS One       Date:  2015-12-31       Impact factor: 3.240

10.  IR-Surviving NSCLC Cells Exhibit Different Patterns of Molecular and Cellular Reactions Relating to the Multifraction Irradiation Regimen and p53-Family Proteins Expression.

Authors:  Lina Alhaddad; Margarita Pustovalova; Taisia Blokhina; Roman Chuprov-Netochin; Andreyan N Osipov; Sergey Leonov
Journal:  Cancers (Basel)       Date:  2021-05-28       Impact factor: 6.639

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