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Literature DB >> 25436585

The molecular biology of selenocysteine.

Jonathan N Gonzalez-Flores, Sumangala P Shetty, Aditi Dubey, Paul R Copeland.

Abstract

Selenium is an essential trace element that is incorporated into 25 human proteins as the amino acid selenocysteine (Sec). The incorporation of this amino acid turns out to be a fascinating problem in molecular biology because Sec is encoded by a stop codon, UGA. Layered on top of the canonical translation elongation machinery is a set of factors that exist solely to incorporate this important amino acid. The mechanism by which this process occurs, put into the context of selenoprotein biology, is the focus of this review.

Entities: CellLine Chemical Disease Gene Species

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Year: 2013 PMID： 25436585 PMCID： PMC4269102 DOI： 10.1515/bmc-2013-0007

Source DB: PubMed Journal: Biomol Concepts ISSN： 1868-5021

147 in total

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Journal: Arch Biochem Biophys Date: 1994-12 Impact factor: 4.013

23 in total

Review 1. Understanding the Genetic Code.

Authors: Milton H Saier
Journal: J Bacteriol Date: 2019-07-10 Impact factor: 3.490

2. ANATOMICAL MNEMONICS OF THE GENETIC CODE: A FUNCTIONAL ICOSAHEDRON AND THE VIGESIMAL SYSTEM OF THE MAYA TO REPRESENT THE TWENTY PROTEINOGENIC AMINO ACIDS.

Authors: Fernando Castro-Chavez
Journal: J Biol Nat Date: 2016

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Authors: Gloria A Brar
Journal: Cell Date: 2016-12-15 Impact factor: 41.582

4. Site-Specific Incorporation of Selenocysteine Using an Expanded Genetic Code and Palladium-Mediated Chemical Deprotection.

Authors: Jun Liu; Feng Zheng; Rujin Cheng; Shanshan Li; Sharon Rozovsky; Qian Wang; Lei Wang
Journal: J Am Chem Soc Date: 2018-07-09 Impact factor: 15.419

5. Selenium-Dependent Read Through of the Conserved 3'-Terminal UGA Stop Codon of HIV-1 nef.

Authors: Lakmini S Premadasa; Gabrielle P Dailey; Jan A Ruzicka; Ethan W Taylor
Journal: Am J Biopharm Pharm Sci Date: 2021-11-01

6. Dietary Serine and Sulfate-Containing Amino Acids Related to the Nutritional Status of Selenium in Lactating Chinese Women.

Authors: Feng Han; Xuehong Pang; Qin Wang; Yiqun Liu; Liping Liu; Yingjuan Chai; Jie Zhang; Shijin Wang; Jiaxi Lu; Licui Sun; Shuo Zhan; Hongying Wu; Zhenwu Huang
Journal: Biol Trace Elem Res Date: 2020-06-12 Impact factor: 3.738

7. Effects of different sources and levels of dietary iron and selenium on the postprandial net portal appearance of these minerals in growing pigs.

Authors: Danyel Bueno Dalto; J Jacques Matte
Journal: J Anim Sci Date: 2020-03-01 Impact factor: 3.159