Literature DB >> 25435735

A prospective study to determine the frequency of bacterial contamination of platelets.

Nagarekha Kulkarni1.   

Abstract

Bacterial contamination of transfusion products is a long standing problem which includes donor bacteremia, contamination during the whole blood collection procedure, contamination of the collection pack and contamination during the blood processing procedure. The purpose of this study is to know the incidence of bacterial contamination of platelets and how to overcome it. During January 2009 to December 2010, 5,000 units of platelets concentrate were collected and 5 ml of platelet concentrate was sent for sterility test. A total of 8 units were reported as bacterially contaminated. Bacterial contamination can be reduced by better skin disinfection, collection of blood with a diversion pouch set, testing for bacteria and potentially the use of safe & effective pathogen reduction technologies and when available.

Entities:  

Keywords:  Bacterial contamination; Platelets; Sterility test

Year:  2013        PMID: 25435735      PMCID: PMC4243404          DOI: 10.1007/s12288-013-0236-5

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN: 0971-4502            Impact factor:   0.900


  9 in total

Review 1.  Don't bug me: the problem of bacterial contamination of blood components--challenges and solutions.

Authors:  M R Jacobs; E Palavecino; R Yomtovian
Journal:  Transfusion       Date:  2001-11       Impact factor: 3.157

2.  A fatal case of transfusion-transmitted Staphylococcus epidermidis sepsis.

Authors:  M Goldman; G Delage; P Beauregard; D Pruneau-Fortier; J Ismaïl; P Robillard
Journal:  Transfusion       Date:  2001-08       Impact factor: 3.157

Review 3.  Bacterial contamination and transfusion safety: experience in the United States.

Authors:  Roger Y Dodd
Journal:  Transfus Clin Biol       Date:  2003-02       Impact factor: 1.406

Review 4.  Bacterial contamination of blood components: risks, strategies, and regulation: joint ASH and AABB educational session in transfusion medicine.

Authors:  Christopher D Hillyer; Cassandra D Josephson; Morris A Blajchman; Jaroslav G Vostal; Jay S Epstein; Jesse L Goodman
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2003

Review 5.  Bacterial contamination in blood components and preventative strategies: an overview.

Authors:  Eugenia Vasconcelos; Jerard Seghatchian
Journal:  Transfus Apher Sci       Date:  2004-10       Impact factor: 1.764

Review 6.  Detecting bacterial contamination in platelet products.

Authors:  Elizabeth L Palavecino; Roslyn A Yomtovian; Michael R Jacobs
Journal:  Clin Lab       Date:  2006       Impact factor: 1.138

7.  The effect of skin disinfection materials on reducing blood culture contamination.

Authors:  R B Schifman; A Pindur
Journal:  Am J Clin Pathol       Date:  1993-05       Impact factor: 2.493

8.  Single-donor platelets reduce the risk of septic platelet transfusion reactions.

Authors:  P Ness; H Braine; K King; C Barrasso; T Kickler; A Fuller; N Blades
Journal:  Transfusion       Date:  2001-07       Impact factor: 3.157

9.  A prospective study of symptomatic bacteremia following platelet transfusion and of its management.

Authors:  E K Chiu; K Y Yuen; A K Lie; R Liang; Y L Lau; A C Lee; Y L Kwong; S Wong; M H Ng; T K Chan
Journal:  Transfusion       Date:  1994 Nov-Dec       Impact factor: 3.157

  9 in total
  2 in total

Review 1.  Skin preparation with alcohol versus alcohol followed by any antiseptic for preventing bacteraemia or contamination of blood for transfusion.

Authors:  Joan Webster; Sally E M Bell-Syer; Ruth Foxlee
Journal:  Cochrane Database Syst Rev       Date:  2015-02-12

2.  Evaluation of bacterial inactivation in random donor platelets and single-donor apheresis platelets by the INTERCEPT blood system.

Authors:  Raj Nath Makroo; Raman Sardana; Leena Mediratta; Hena Butta; Uday Kumar Thakur; Soma Agrawal; Mohit Chowdhry; Satendra Kumar; Sourit Chokroborty
Journal:  Asian J Transfus Sci       Date:  2018 Jul-Dec
  2 in total

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