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Literature DB >> 2543438

Intravitreal ganciclovir in CMV retinitis: case report.

M L Harris¹, M B Mathalone.
1. St Stephen's Hospital, London.

Abstract

A case is reported of a 35-year-old male with established acquired immune deficiency syndrome who developed cytomegalovirus retinitis. When intravenous treatment with ganciclovir had to be withdrawn because of toxicity, one eye was treated successfully by intravitreal injections of the drug. After 15 weeks of intravitreal treatment this eye developed endophthalmitis.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1989 PMID： 2543438 PMCID： PMC1041746 DOI： 10.1136/bjo.73.5.382

Source DB: PubMed Journal: Br J Ophthalmol ISSN： 0007-1161 Impact factor: 4.638

12 in total

1. Treatment of cytomegalovirus retinitis with ganciclovir.

Authors: D A Jabs; C Newman; S De Bustros; B F Polk
Journal: Ophthalmology Date: 1987-07 Impact factor: 12.079

2. Dihydroxypropoxymethyl guanine in the treatment of AIDS related retinitis due to cytomegalovirus.

Authors: M L Harris; M B Mathalone
Journal: Br Med J (Clin Res Ed) Date: 1987-01-10

Review 3. Acquired immunodeficiency syndrome (AIDS): the disease and its ocular manifestations.

Authors: J A Mines; H J Kaplan
Journal: Int Ophthalmol Clin Date: 1986

4. Intravitreal toxicity of hydroxyacyclovir (BW-B759U), a new antiviral agent.

Authors: J Pulido; G A Peyman; T Lesar; J Vernot
Journal: Arch Ophthalmol Date: 1985-06

5. Ophthalmic involvement in acquired immunodeficiency syndrome.

Authors: A G Palestine; M M Rodrigues; A M Macher; C C Chan; H C Lane; A S Fauci; H Masur; D Longo; C M Reichert; R Steis
Journal: Ophthalmology Date: 1984-09 Impact factor: 12.079

6. Cytomegalovirus retinitis and response to therapy with ganciclovir.

Authors: D E Henderly; W R Freeman; D M Causey; N A Rao
Journal: Ophthalmology Date: 1987-04 Impact factor: 12.079

7. Use of intravitreal ganciclovir (dihydroxy propoxymethyl guanine) for cytomegalovirus retinitis in a patient with AIDS.

Authors: K Henry; H Cantrill; C Fletcher; B J Chinnock; H H Balfour
Journal: Am J Ophthalmol Date: 1987-01-15 Impact factor: 5.258

8. Ophthalmologic findings in acquired immune deficiency syndrome (AIDS).

Authors: M Khadem; S B Kalish; J Goldsmith; C Fetkenhour; R B O'Grady; J P Phair; M Chrobak
Journal: Arch Ophthalmol Date: 1984-02

9. Etiology and diagnosis of bacterial postoperative endophthalmitis.

Authors: R K Forster
Journal: Ophthalmology Date: 1978-04 Impact factor: 12.079

10. Infectious endophthalmitis. Review of 36 cases.

Authors: C A Puliafito; A S Baker; J Haaf; C S Foster
Journal: Ophthalmology Date: 1982-08 Impact factor: 12.079

5 in total

1. Intravitreal therapy with ganciclovir for posterior pole cytomegalovirus retinitis in AIDS patients.

Authors: J Orellana; R M Lieberman; R Peairs; S Restreppo
Journal: Br J Ophthalmol Date: 1990-08 Impact factor: 4.638

2. Treatment of cytomegalovirus retinitis with intravitreal injection of liposome encapsulated ganciclovir in a patient with AIDS.

Authors: S K Akula; P E Ma; G A Peyman; M H Rahimy; N E Hyslop; A Janney; P Ashton
Journal: Br J Ophthalmol Date: 1994-09 Impact factor: 4.638

3. Treatment of cytomegalovirus retinitis with zidovudine and ganciclovir in patients with AIDS: outcome and toxicity.

Authors: A B Millar; R F Miller; G Patou; A Mindel; R Marsh; S J Semple
Journal: Genitourin Med Date: 1990-06

Review 4. Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infections.

Authors: D Faulds; R C Heel
Journal: Drugs Date: 1990-04 Impact factor: 9.546

Review 5. Ocular complications of the acquired immunodeficiency syndrome. Focus on the treatment of cytomegalovirus retinitis with ganciclovir and foscarnet.

Authors: W J Keijer; D M Burger; G H Neuteboom; J L Vrooland; P L Meenhorst; C H Koks; J H Beijnen
Journal: Pharm World Sci Date: 1993-04-23

5 in total