Literature DB >> 25426316

CMOS image sensor-based implantable glucose sensor using glucose-responsive fluorescent hydrogel.

Takashi Tokuda1, Masayuki Takahashi2, Kazuhiro Uejima1, Keita Masuda1, Toshikazu Kawamura1, Yasumi Ohta1, Mayumi Motoyama1, Toshihiko Noda1, Kiyotaka Sasagawa1, Teru Okitsu3, Shoji Takeuchi3, Jun Ohta1.   

Abstract

A CMOS image sensor-based implantable glucose sensor based on an optical-sensing scheme is proposed and experimentally verified. A glucose-responsive fluorescent hydrogel is used as the mediator in the measurement scheme. The wired implantable glucose sensor was realized by integrating a CMOS image sensor, hydrogel, UV light emitting diodes, and an optical filter on a flexible polyimide substrate. Feasibility of the glucose sensor was verified by both in vitro and in vivo experiments.

Entities:  

Keywords:  (000.0000) General; (000.2700) General science

Year:  2014        PMID： 25426316      PMCID： PMC4242023          DOI： 10.1364/BOE.5.003859

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN： 2156-7085            Impact factor:   3.732


  10 in total

1.  Novel implantable imaging system for enabling simultaneous multiplanar and multipoint analysis for fluorescence potentiometry in the visual cortex.

Authors:  Takuma Kobayashi; Mayumi Motoyama; Hiroyuki Masuda; Yasumi Ohta; Makito Haruta; Toshihiko Noda; Kiyotaka Sasagawa; Takashi Tokuda; Hideki Tamura; Yasuyuki Ishikawa; Sadao Shiosaka; Jun Ohta
Journal:  Biosens Bioelectron       Date:  2012-06-29       Impact factor: 10.618

2.  Injectable hydrogel microbeads for fluorescence-based in vivo continuous glucose monitoring.

Authors:  Hideaki Shibata; Yun Jung Heo; Teru Okitsu; Yukiko Matsunaga; Tetsuro Kawanishi; Shoji Takeuchi
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-04       Impact factor: 11.205

Review 3.  Home blood glucose biosensors: a commercial perspective.

Authors:  Jeffrey D Newman; Anthony P F Turner
Journal:  Biosens Bioelectron       Date:  2005-01-18       Impact factor: 10.618

4.  A study of boronic acid based fluorescent glucose sensors.

Authors:  T Kawanishi; M A Romey; P C Zhu; M Z Holody; S Shinkai
Journal:  J Fluoresc       Date:  2004-09       Impact factor: 2.217

5.  A wireless-implantable microsystem for continuous blood glucose monitoring.

Authors:  M M Ahmadi; G A Jullien
Journal:  IEEE Trans Biomed Circuits Syst       Date:  2009-06       Impact factor: 3.833

6.  Functional brain fluorescence plurimetry in rat by implantable concatenated CMOS imaging system.

Authors:  Takuma Kobayashi; Hiroyuki Masuda; Chikara Kitsumoto; Makito Haruta; Mayumi Motoyama; Yasumi Ohta; Toshihiko Noda; Kiyotaka Sasagawa; Takashi Tokuda; Sadao Shiosaka; Jun Ohta
Journal:  Biosens Bioelectron       Date:  2013-09-21       Impact factor: 10.618

7.  A telemetry-instrumentation system for monitoring multiple subcutaneously implanted glucose sensors.

Authors:  M C Shults; R K Rhodes; S J Updike; B J Gilligan; W N Reining
Journal:  IEEE Trans Biomed Eng       Date:  1994-10       Impact factor: 4.538

8.  Long-term in vivo glucose monitoring using fluorescent hydrogel fibers.

Authors:  Yun Jung Heo; Hideaki Shibata; Teru Okitsu; Tetsuro Kawanishi; Shoji Takeuchi
Journal:  Proc Natl Acad Sci U S A       Date:  2011-08-01       Impact factor: 11.205

9.  Soft contact lens biosensor for in situ monitoring of tear glucose as non-invasive blood sugar assessment.

Authors:  Ming Xing Chu; Kumiko Miyajima; Daishi Takahashi; Takahiro Arakawa; Kenji Sano; Shin-ichi Sawada; Hiroyuki Kudo; Yasuhiko Iwasaki; Kazunari Akiyoshi; Manabu Mochizuki; Kohji Mitsubayashi
Journal:  Talanta       Date:  2010-11-04       Impact factor: 6.057

Review 10.  Estimating plasma glucose from interstitial glucose: the issue of calibration algorithms in commercial continuous glucose monitoring devices.

Authors:  Paolo Rossetti; Jorge Bondia; Josep Vehí; Carmine G Fanelli
Journal:  Sensors (Basel)       Date:  2010-12-03       Impact factor: 3.576
  10 in total
  6 in total

1.  A hydrogel-based glucose affinity microsensor.

Authors:  Junyi Shang; Jing Yan; Zhixing Zhang; Xian Huang; Panita Maturavongsadit; Bing Song; Yuan Jia; Tieying Ma; Dachao Li; Kexin Xu; Qian Wang; Qiao Lin
Journal:  Sens Actuators B Chem       Date:  2016-03-29       Impact factor: 7.460

2.  Repeatable detection of Ag+ ions using a DNA aptamer-linked hydrogel biochemical sensor integrated with microfluidic heating system.

Authors:  Koki Yoshida; Tomoki Hayashi; Masahiro Takinoue; Hiroaki Onoe
Journal:  Sci Rep       Date:  2022-06-11       Impact factor: 4.996

Review 3.  New Bioengineering Breakthroughs and Enabling Tools in Regenerative Medicine.

Authors:  Alvaro Mata; Helena S Azevedo; Lorenzo Botto; Nuria Gavara; Lei Su
Journal:  Curr Stem Cell Rep       Date:  2017-05-04

Review 4.  In-Vivo Microsystems: A Review.

Authors:  Paddy French
Journal:  Sensors (Basel)       Date:  2020-09-01       Impact factor: 3.576

5.  Batteryless, Miniaturized Implantable Glucose Sensor Using a Fluorescent Hydrogel.

Authors:  Hyeonkeon Lee; Jongheon Lee; Honghyeon Park; Mi Song Nam; Yun Jung Heo; Sanghoek Kim
Journal:  Sensors (Basel)       Date:  2021-12-18       Impact factor: 3.576

6.  Neural Monitoring With CMOS Image Sensors.

Authors:  Azar Yadegari; Mohammad Azim Karami; Mohammad Reza Daliri
Journal:  Basic Clin Neurosci       Date:  2018 May-Jun
  6 in total

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