Literature DB >> 25425652

Early onset neonatal sepsis: diagnostic dilemmas and practical management.

A R Bedford Russell1, R Kumar1.   

Abstract

Early onset neonatal sepsis is persistently associated with poor outcomes, and incites clinical practice based on the fear of missing a treatable infection in a timely fashion. Unnecessary exposure to antibiotics is also hazardous. Diagnostic dilemmas are discussed in this review, and suggestions offered for practical management while awaiting a more rapidly available 'gold standard' test; in an ideal world, this test would be 100% sensitive and 100% specific for the presence of organisms. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Entities:  

Keywords:  Evidence Based Medicine; Immunology; Infectious Diseases; Microbiology; Neonatology

Mesh：

Substances：

Year:  2014        PMID： 25425652     DOI： 10.1136/archdischild-2014-306193

Source DB:  PubMed          Journal:  Arch Dis Child Fetal Neonatal Ed        ISSN： 1359-2998            Impact factor:   5.747


  18 in total

1.  Race, Income and Insurance Status Affect Neonatal Sepsis Mortality and Healthcare Resource Utilization.

Authors:  Fredrick J Bohanon; Omar Nunez Lopez; Deepak Adhikari; Hemalkumar B Mehta; Yesenia Rojas-Khalil; Kanika A Bowen-Jallow; Ravi S Radhakrishnan
Journal:  Pediatr Infect Dis J       Date:  2018-07       Impact factor: 2.129

2.  Effects of local anesthetics on the respiratory burst of cord blood neutrophils in vitro.

Authors:  Hanna Billert; Katarzyna Czerniak; Ewa Bednarek; Karolina Kulińska
Journal:  Pediatr Res       Date:  2016-04-07       Impact factor: 3.756

3.  Negative Temperature Differential in Preterm Infants Less Than 29 Weeks Gestational Age: Associations With Infection and Maternal Smoking.

Authors:  Robin B Knobel-Dail; Richard Sloane; Diane Holditch-Davis; David T Tanaka
Journal:  Nurs Res       Date:  2017 Nov/Dec       Impact factor: 2.381

Review 4.  The Potential Role of Fosfomycin in Neonatal Sepsis Caused by Multidrug-Resistant Bacteria.

Authors:  Grace Li; Joseph F Standing; Julia Bielicki; William Hope; John van den Anker; Paul T Heath; Mike Sharland
Journal:  Drugs       Date:  2017-06       Impact factor: 9.546

Review 5.  Defining neonatal sepsis.

Authors:  James L Wynn
Journal:  Curr Opin Pediatr       Date:  2016-04       Impact factor: 2.856

6.  Lung ultrasound in diagnosing pneumonia in childhood: a systematic review and meta-analysis.

Authors:  Daniele Orso; Alessio Ban; Nicola Guglielmo
Journal:  J Ultrasound       Date:  2018-06-21

Review 7.  Group B Streptococcus vaccine development: present status and future considerations, with emphasis on perspectives for low and middle income countries.

Authors:  Miwako Kobayashi; Johan Vekemans; Carol J Baker; Adam J Ratner; Kirsty Le Doare; Stephanie J Schrag
Journal:  F1000Res       Date:  2016-09-22

8.  Antibiotic regimens for late-onset neonatal sepsis.

Authors:  Steven Kwasi Korang; Sanam Safi; Chiara Nava; Gorm Greisen; Munish Gupta; Ulrik Lausten-Thomsen; Janus C Jakobsen
Journal:  Cochrane Database Syst Rev       Date:  2021-05-08

9.  Antibiotic regimens for early-onset neonatal sepsis.

Authors:  Steven Kwasi Korang; Sanam Safi; Chiara Nava; Adrienne Gordon; Munish Gupta; Gorm Greisen; Ulrik Lausten-Thomsen; Janus C Jakobsen
Journal:  Cochrane Database Syst Rev       Date:  2021-05-17

10.  Neonatal infections: Case definition and guidelines for data collection, analysis, and presentation of immunisation safety data.

Authors:  Stefania Vergnano; Jim Buttery; Ben Cailes; Ravichandran Chandrasekaran; Elena Chiappini; Ebiere Clark; Clare Cutland; Solange Dourado de Andrade; Alejandra Esteves-Jaramillo; Javier Ruiz Guinazu; Chrissie Jones; Beate Kampmann; Jay King; Sonali Kochhar; Noni Macdonald; Alexandra Mangili; Reinaldo de Menezes Martins; César Velasco Muñoz; Michael Padula; Flor M Muñoz; James Oleske; Melvin Sanicas; Elizabeth Schlaudecker; Hans Spiegel; Maja Subelj; Lakshmi Sukumaran; Beckie N Tagbo; Karina A Top; Dat Tran; Paul T Heath
Journal:  Vaccine       Date:  2016-08-01       Impact factor: 3.641
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