Literature DB >> 25424562

Fused aortic valve without an elliptical-shaped systolic orifice in patients with severe aortic stenosis: cardiac computed tomography is useful for differentiation between bicuspid aortic valve with raphe and tricuspid aortic valve with commissural fusion.

So Hyeon Bak1, Sung Min Ko, Meong Gun Song, Je Kyoun Shin, Hyun Kun Chee, Jun Suk Kim.   

Abstract

OBJECTIVE: The objective is to determine cardiac computed tomography (CCT) features capable of differentiating between bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV) in severe aortic stenosis (AS) patients with fused cusp and without elliptical-shaped systolic orifices.
METHODS: We retrospectively enrolled 53 patients who had severe AS with fused cusps and without an elliptical-shaped systolic orifice on CCT and who had undergone surgery. CCT features were analyzed using: 1) aortic valve findings including cusp size, cusp area, opening shape, midline calcification, fusion length, calcium volume score, and calcium grade; 2) diameters of ascending and descending aorta, and main pulmonary artery; and 3) rheumatic mitral valve findings. The variables were evaluated using univariate and multivariate logistic regression analyses.
RESULTS: At surgery, 19 patients had BAV and 34 had TAV. CCT features including uneven cusp size, uneven cusp area, round-shaped systolic orifice, longer cusp fusion, and dilatation of ascending aorta were significantly associated with BAV (P < 0.05). In particular, fusion length (OR, 1.76; P = 0.001), uneven cusp area (OR, 10.46; P = 0.012), and midline calcification (OR, 0.08; P = 0.013) were strongly associated with BAV.
CONCLUSION: CCT provides diagnostic clues that helps differentiate between BAV with raphe and TAV with commissural fusion in patients with severe AS. KEY POINTS: • Accurate morphologic assessment of the aortic valve is important for treatment planning. • It is difficult to differentiate BAV from TAV with a fused cusp. • CCT provides diagnostic clues for the differentiation of BAV and TAV.

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Year:  2014        PMID: 25424562     DOI: 10.1007/s00330-014-3494-1

Source DB:  PubMed          Journal:  Eur Radiol        ISSN: 0938-7994            Impact factor:   5.315


  33 in total

Review 1.  Radiation dose in computed tomography of the heart.

Authors:  Richard L Morin; Thomas C Gerber; Cynthia H McCollough
Journal:  Circulation       Date:  2003-02-18       Impact factor: 29.690

Review 2.  Rheumatic heart disease.

Authors:  Eloi Marijon; Mariana Mirabel; David S Celermajer; Xavier Jouven
Journal:  Lancet       Date:  2012-03-10       Impact factor: 79.321

Review 3.  Vascular calcification: pathobiology of a multifaceted disease.

Authors:  Linda L Demer; Yin Tintut
Journal:  Circulation       Date:  2008-06-03       Impact factor: 29.690

4.  Bicuspid aortic valve and aortopathy: see the first, then look at the second.

Authors:  Rosario V Freeman; Catherine M Otto
Journal:  JACC Cardiovasc Imaging       Date:  2013-02

5.  Interobserver variability of CT angiography for evaluation of aortic annulus dimensions prior to transcatheter aortic valve implantation (TAVI).

Authors:  C Schmidkonz; M Marwan; L Klinghammer; M Mitschke; A Schuhbaeck; M Arnold; M Lell; S Achenbach; T Pflederer
Journal:  Eur J Radiol       Date:  2014-06-19       Impact factor: 3.528

6.  Incidental aortic valve calcification on CT scans: significance for bicuspid and tricuspid valve disease.

Authors:  Michael D Hope; Thomas H Urbania; John-Paul J Yu; Sam Chitsaz; Elaine Tseng
Journal:  Acad Radiol       Date:  2011-11-21       Impact factor: 3.173

7.  Variable phenotypes of bicuspid aortic valve disease: classification by cardiovascular magnetic resonance.

Authors:  Stefan Buchner; Marion Hülsmann; Florian Poschenrieder; Okka W Hamer; Claudia Fellner; Reinhard Kobuch; Stefan Feuerbach; Günter A J Riegger; Behrus Djavidani; Andreas Luchner; Kurt Debl
Journal:  Heart       Date:  2010-06-15       Impact factor: 5.994

8.  Main pulmonary artery dilation in association with congenital bicuspid aortic valve in the absence of pulmonary valve abnormality.

Authors:  Shelby Kutty; Sheetal Kaul; Christopher J Danford; David A Danford
Journal:  Heart       Date:  2010-11       Impact factor: 5.994

Review 9.  Evaluation of valvular disease by cardiac computed tomography assessment.

Authors:  Anshu K Buttan; Eric H Yang; Matthew J Budoff; Gabriel Vorobiof
Journal:  J Cardiovasc Comput Tomogr       Date:  2012-11-03

Review 10.  Calcific aortic stenosis: lessons learned from experimental and clinical studies.

Authors:  Nalini M Rajamannan
Journal:  Arterioscler Thromb Vasc Biol       Date:  2008-11-20       Impact factor: 8.311

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  1 in total

1.  Morphological and Functional Evaluation of Quadricuspid Aortic Valves Using Cardiac Computed Tomography.

Authors:  Inyoung Song; Jung Ah Park; Bo Hwa Choi; Sung Min Ko; Je Kyoun Shin; Hyun Keun Chee; Jun Seok Kim
Journal:  Korean J Radiol       Date:  2016-06-27       Impact factor: 3.500

  1 in total

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