BACKGROUND AND OBJECTIVE: To investigate the potential of ultrahigh-speed swept-source optical coherence tomography angiography (OCTA) to visualize retinal and choroidal vascular changes in patients with exudative age-related macular degeneration (AMD). PATIENTS AND METHODS: Observational, prospective cross-sectional study. An ultrahigh-speed swept-source prototype was used to perform OCTA of the retinal and choriocapillaris microvasculature in 63 eyes of 32 healthy controls and 19 eyes of 15 patients with exudative AMD. MAIN OUTCOME MEASURE: qualitative comparison of the retinal and choriocapillaris microvasculature in the two groups. RESULTS: Choroidal neovascularization (CNV) was clearly visualized in 16 of the 19 eyes with exudative AMD, located above regions of severe choriocapillaris alteration. In 14 of these eyes, the CNV lesions were surrounded by regions of choriocapillaris alteration. CONCLUSION: OCTA may offer noninvasive monitoring of the retinal and choriocapillaris microvasculature in patients with CNV, which may assist in diagnosis and monitoring. Copyright 2014, SLACK Incorporated.
BACKGROUND AND OBJECTIVE: To investigate the potential of ultrahigh-speed swept-source optical coherence tomography angiography (OCTA) to visualize retinal and choroidal vascular changes in patients with exudative age-related macular degeneration (AMD). PATIENTS AND METHODS: Observational, prospective cross-sectional study. An ultrahigh-speed swept-source prototype was used to perform OCTA of the retinal and choriocapillaris microvasculature in 63 eyes of 32 healthy controls and 19 eyes of 15 patients with exudative AMD. MAIN OUTCOME MEASURE: qualitative comparison of the retinal and choriocapillaris microvasculature in the two groups. RESULTS: Choroidal neovascularization (CNV) was clearly visualized in 16 of the 19 eyes with exudative AMD, located above regions of severe choriocapillaris alteration. In 14 of these eyes, the CNV lesions were surrounded by regions of choriocapillaris alteration. CONCLUSION:OCTA may offer noninvasive monitoring of the retinal and choriocapillaris microvasculature in patients with CNV, which may assist in diagnosis and monitoring. Copyright 2014, SLACK Incorporated.
Authors: Geeta A Lalwani; Philip J Rosenfeld; Anne E Fung; Sander R Dubovy; Stephen Michels; William Feuer; Janet L Davis; Harry W Flynn; Maria Esquiabro Journal: Am J Ophthalmol Date: 2009-04-18 Impact factor: 5.258
Authors: Benjamin J Vakoc; Ryan M Lanning; James A Tyrrell; Timothy P Padera; Lisa A Bartlett; Triantafyllos Stylianopoulos; Lance L Munn; Guillermo J Tearney; Dai Fukumura; Rakesh K Jain; Brett E Bouma Journal: Nat Med Date: 2009-09-13 Impact factor: 53.440
Authors: WooJhon Choi; Eric M Moult; Nadia K Waheed; Mehreen Adhi; ByungKun Lee; Chen D Lu; Talisa E de Carlo; Vijaysekhar Jayaraman; Philip J Rosenfeld; Jay S Duker; James G Fujimoto Journal: Ophthalmology Date: 2015-10-17 Impact factor: 12.079
Authors: Leonardo Mastropasqua; Enrico Borrelli; Paolo Carpineto; Lisa Toto; Luca Di Antonio; Peter A Mattei; Rodolfo Mastropasqua Journal: Int Ophthalmol Date: 2017-06-19 Impact factor: 2.031
Authors: Jin Yang; Qinqin Zhang; Elie H Motulsky; Marie Thulliez; Yingying Shi; Cancan Lyu; Luis de Sisternes; Mary K Durbin; William Feuer; Ruikang K Wang; Giovanni Gregori; Philip J Rosenfeld Journal: Am J Ophthalmol Date: 2019-06-21 Impact factor: 5.258
Authors: David A Salz; Talisa E de Carlo; Mehreen Adhi; Eric Moult; WhooJhon Choi; Caroline R Baumal; Andre J Witkin; Jay S Duker; James G Fujimoto; Nadia K Waheed Journal: JAMA Ophthalmol Date: 2016-06-01 Impact factor: 7.389
Authors: Tristan T Hormel; Jie Wang; Steven T Bailey; Thomas S Hwang; David Huang; Yali Jia Journal: Biomed Opt Express Date: 2018-11-26 Impact factor: 3.732