Leonardo Mastropasqua1, Enrico Borrelli2, Paolo Carpineto1, Lisa Toto1, Luca Di Antonio1, Peter A Mattei1, Rodolfo Mastropasqua3. 1. Ophthalmology Clinic, Department of Medicine and Science of Ageing, University G. D'Annunzio Chieti-Pescara, Chieti, Italy. 2. Ophthalmology Clinic, Department of Medicine and Science of Ageing, University G. D'Annunzio Chieti-Pescara, Chieti, Italy. borrelli.enrico@yahoo.com. 3. Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Abstract
PURPOSE: To evaluate superficial capillary plexus (SCP) changes occurring after internal limiting membrane (ILM) peeling for the treatment of idiopathic epiretinal membrane (ERM). METHODS: A total of 15 eyes of 15 patients affected by idiopathic ERM (eight males and seven females; mean age 59.8 ± 9.6 years) were enrolled in the study. Patients were treated with pars plana vitrectomy followed by ERM and ILM peeling. Subjects were evaluated at baseline and at the week-1 and month-1 follow-up visits. At each visit, patients were evaluated with a complete ophthalmologic evaluation, which included imaging with optical coherence tomography angiography. RESULTS: Overall, the SCP vessel density was 43.0 ± 3.0% at baseline and was stable throughout the follow-up (40.0 ± 4.0% at week-1 and 41.0 ± 4.0% at month-1 follow-up visits; p = 0.087 and p = 0.426, respectively). Nevertheless, the SCP vessel density was reduced at week-1 visit in both the superior and inferior sectors. In these sectors, the superficial vessel density was still reduced at the month-1 follow-up visit. CONCLUSIONS: We observed a reduction in the SCP vessel density occurring after pars plana vitrectomy with ILM peeling. The reduction is referred to those areas where other changes (e.g., swelling of the arcuate nerve fiber layer) have been already described. In theory, superficial vessel density modifications may be due to the direct surgical trauma to the inner retina, where the superficial plexus is contained, during the ILM grasping.
PURPOSE: To evaluate superficial capillary plexus (SCP) changes occurring after internal limiting membrane (ILM) peeling for the treatment of idiopathic epiretinal membrane (ERM). METHODS: A total of 15 eyes of 15patients affected by idiopathic ERM (eight males and seven females; mean age 59.8 ± 9.6 years) were enrolled in the study. Patients were treated with pars plana vitrectomy followed by ERM and ILM peeling. Subjects were evaluated at baseline and at the week-1 and month-1 follow-up visits. At each visit, patients were evaluated with a complete ophthalmologic evaluation, which included imaging with optical coherence tomography angiography. RESULTS: Overall, the SCP vessel density was 43.0 ± 3.0% at baseline and was stable throughout the follow-up (40.0 ± 4.0% at week-1 and 41.0 ± 4.0% at month-1 follow-up visits; p = 0.087 and p = 0.426, respectively). Nevertheless, the SCP vessel density was reduced at week-1 visit in both the superior and inferior sectors. In these sectors, the superficial vessel density was still reduced at the month-1 follow-up visit. CONCLUSIONS: We observed a reduction in the SCP vessel density occurring after pars plana vitrectomy with ILM peeling. The reduction is referred to those areas where other changes (e.g., swelling of the arcuate nerve fiber layer) have been already described. In theory, superficial vessel density modifications may be due to the direct surgical trauma to the inner retina, where the superficial plexus is contained, during the ILM grasping.
Entities:
Keywords:
ILM peeling; OCT; OCT angiography; OCTA; Vitrectomy
Authors: Yanping Huang; Qinqin Zhang; Mariana R Thorell; Lin An; Mary K Durbin; Michal Laron; Utkarsh Sharma; Giovanni Gregori; Philip J Rosenfeld; Ruikang K Wang Journal: Ophthalmic Surg Lasers Imaging Retina Date: 2014 Sep-Oct Impact factor: 1.300
Authors: Francesco Pichi; Andrea Lembo; Mariachiara Morara; Chiara Veronese; Micol Alkabes; Paolo Nucci; Antonio P Ciardella Journal: Int Ophthalmol Date: 2013-07-18 Impact factor: 2.031
Authors: Donald W Park; Pravin U Dugel; Jennifer Garda; Jack O Sipperley; Allen Thach; Scott R Sneed; Jennifer Blaisdell Journal: Ophthalmology Date: 2003-01 Impact factor: 12.079
Authors: Lorenzo Iuliano; Erika Kacerik; Eleonora Corbelli; Francesco Bandello; Marco Codenotti Journal: Int Ophthalmol Date: 2021-01-03 Impact factor: 2.031
Authors: Lorenzo Iuliano; Giovanni Fogliato; Roberta Colombo; Riccardo Sacconi; Giuseppe Querques; Francesco Bandello; Marco Codenotti Journal: BMC Ophthalmol Date: 2019-05-10 Impact factor: 2.209
Authors: Daniela Bacherini; Francesco Dragotto; Tomaso Caporossi; Chiara Lenzetti; Lucia Finocchio; Alfonso Savastano; Maria Cristina Savastano; Francesco Barca; Martina Dragotto; Lorenzo Vannozzi; Francesco Nasini; Francesco Faraldi; Stanislao Rizzo; Gianni Virgili; Fabrizio Giansanti Journal: J Ophthalmol Date: 2021-03-24 Impact factor: 1.909