Literature DB >> 25419698

Outcomes after out-of-hospital cardiac arrest treated by basic vs advanced life support.

Prachi Sanghavi1, Anupam B Jena2, Joseph P Newhouse3, Alan M Zaslavsky4.   

Abstract

IMPORTANCE: Most out-of-hospital cardiac arrests receiving emergency medical services in the United States are treated by ambulance service providers trained in advanced life support (ALS), but supporting evidence for the use of ALS over basic life support (BLS) is limited.
OBJECTIVE: To compare the effects of BLS and ALS on outcomes after out-of-hospital cardiac arrest. DESIGN, SETTING, AND PARTICIPANTS: Observational cohort study of a nationally representative sample of traditional Medicare beneficiaries from nonrural counties who experienced out-of-hospital cardiac arrest between January 1, 2009, and October 2, 2011, and for whom ALS or BLS ambulance services were billed to Medicare (31,292 ALS cases and 1643 BLS cases). Propensity score methods were used to compare the effects of ALS and BLS on patient survival, neurological performance, and medical spending after cardiac arrest. MAIN OUTCOMES AND MEASURES: Survival to hospital discharge, to 30 days, and to 90 days; neurological performance; and incremental medical spending per additional survivor to 1 year.
RESULTS: Survival to hospital discharge was greater among patients receiving BLS (13.1% vs 9.2% for ALS; 4.0 [95% CI, 2.3-5.7] percentage point difference), as was survival to 90 days (8.0% vs 5.4% for ALS; 2.6 [95% CI, 1.2-4.0] percentage point difference). Basic life support was associated with better neurological functioning among hospitalized patients (21.8% vs 44.8% with poor neurological functioning for ALS; 23.0 [95% CI, 18.6-27.4] percentage point difference). Incremental medical spending per additional survivor to 1 year for BLS relative to ALS was $154,333. CONCLUSIONS AND RELEVANCE: Patients with out-of-hospital cardiac arrest who received BLS had higher survival at hospital discharge and at 90 days compared with those who received ALS and were less likely to experience poor neurological functioning.

Entities:  

Mesh:

Year:  2015        PMID: 25419698      PMCID: PMC4314335          DOI: 10.1001/jamainternmed.2014.5420

Source DB:  PubMed          Journal:  JAMA Intern Med        ISSN: 2168-6106            Impact factor:   21.873


  27 in total

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Authors:  Ian G Stiell; George A Wells; Brian Field; Daniel W Spaite; Lisa P Nesbitt; Valerie J De Maio; Graham Nichol; Donna Cousineau; Josée Blackburn; Doug Munkley; Lorraine Luinstra-Toohey; Tony Campeau; Eugene Dagnone; Marion Lyver
Journal:  N Engl J Med       Date:  2004-08-12       Impact factor: 91.245

2.  Managing the airway during cardiac arrest.

Authors:  Henry E Wang; Donald M Yealy
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3.  Effects of bystander first aid, defibrillation and advanced life support on neurologic outcome and hospital costs in patients after ventricular fibrillation cardiac arrest.

Authors:  A Bur; H Kittler; F Sterz; M Holzer; P Eisenburger; E Oschatz; J Kofler; A N Laggner
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4.  Association of drug therapy with survival in cardiac arrest: limited role of advanced cardiac life support drugs.

Authors:  I G Stiell; G A Wells; P C Hebert; A Laupacis; B N Weitzman
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Review 5.  Advanced life support drugs: do they really work?

Authors:  Jerry P Nolan; Francisco J De Latorre; Petter A Steen; Douglas A Chamberlain; Leo L Bossaert
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6.  Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest.

Authors: 
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7.  Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia.

Authors:  Stephen A Bernard; Timothy W Gray; Michael D Buist; Bruce M Jones; William Silvester; Geoff Gutteridge; Karen Smith
Journal:  N Engl J Med       Date:  2002-02-21       Impact factor: 91.245

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9.  Association of neighborhood characteristics with bystander-initiated CPR.

Authors:  Comilla Sasson; David J Magid; Paul Chan; Elisabeth D Root; Bryan F McNally; Arthur L Kellermann; Jason S Haukoos
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10.  Public-access defibrillation and survival after out-of-hospital cardiac arrest.

Authors:  A P Hallstrom; J P Ornato; M Weisfeldt; A Travers; J Christenson; M A McBurnie; R Zalenski; L B Becker; E B Schron; M Proschan
Journal:  N Engl J Med       Date:  2004-08-12       Impact factor: 91.245

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2.  Geographic Variation in Use of Ambulance Transport to the Emergency Department.

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3.  Long-term Survival After Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-analysis.

Authors:  Simon A Amacher; Chantal Bohren; René Blatter; Christoph Becker; Katharina Beck; Jonas Mueller; Nina Loretz; Sebastian Gross; Kai Tisljar; Raoul Sutter; Christian Appenzeller-Herzog; Stephan Marsch; Sabina Hunziker
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4.  Effect of Bag-Mask Ventilation vs Endotracheal Intubation During Cardiopulmonary Resuscitation on Neurological Outcome After Out-of-Hospital Cardiorespiratory Arrest: A Randomized Clinical Trial.

Authors:  Patricia Jabre; Andrea Penaloza; David Pinero; Francois-Xavier Duchateau; Stephen W Borron; Francois Javaudin; Olivier Richard; Diane de Longueville; Guillem Bouilleau; Marie-Laure Devaud; Matthieu Heidet; Caroline Lejeune; Sophie Fauroux; Jean-Luc Greingor; Alessandro Manara; Jean-Christophe Hubert; Bertrand Guihard; Olivier Vermylen; Pascale Lievens; Yannick Auffret; Celine Maisondieu; Stephanie Huet; Benoît Claessens; Frederic Lapostolle; Nicolas Javaud; Paul-Georges Reuter; Elinor Baker; Eric Vicaut; Frédéric Adnet
Journal:  JAMA       Date:  2018-02-27       Impact factor: 56.272

5.  Outcomes of Basic Versus Advanced Life Support for Out-of-Hospital Medical Emergencies.

Authors:  Prachi Sanghavi; Anupam B Jena; Joseph P Newhouse; Alan M Zaslavsky
Journal:  Ann Intern Med       Date:  2015-10-13       Impact factor: 25.391

6.  Association of early withdrawal of life-sustaining therapy for perceived neurological prognosis with mortality after cardiac arrest.

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7.  Association of Prehospital Advanced Life Support by Physician With Survival After Out-of-Hospital Cardiac Arrest With Blunt Trauma Following Traffic Collisions: Japanese Registry-Based Study.

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8.  Seasonal variation in incidence and outcomes of out of hospital cardiac arrest: A retrospective national observational study in the United States.

Authors:  Rayan H El Sibai; Rana H Bachir; Mazen J El Sayed
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9.  A national assessment of legacy versus new generation Medicaid data.

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10.  A randomized trial of the effects of the noble gases helium and argon on neuroprotection in a rodent cardiac arrest model.

Authors:  Patrick Zuercher; Dirk Springe; Denis Grandgirard; Stephen L Leib; Marius Grossholz; Stephan Jakob; Jukka Takala; Matthias Haenggi
Journal:  BMC Neurol       Date:  2016-04-04       Impact factor: 2.474

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