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Literature DB >> 2541657

Fleroxacin resistance in Escherichia coli.

J S Chapman¹, A Bertasso, N H Georgopapadakou.

Abstract

Spontaneous fleroxacin-resistant mutants of Escherichia coli K-12 were isolated at a frequency of 10(-10) to 10(-11) mutants per CFU plated. All mutants exhibited quinolone-resistant replicative DNA biosynthesis, and 4 of 11 mutants also had decreased amounts of OmpF or OmpC porin. None of the mutants had changes solely in porin proteins.

Entities: Chemical Species

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Year: 1989 PMID： 2541657 PMCID： PMC171465 DOI： 10.1128/AAC.33.2.239

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

13 in total

1. The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro.

Authors: J S Wolfson; D C Hooper
Journal: Antimicrob Agents Chemother Date: 1985-10 Impact factor: 5.191

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Authors: P J Bassford; D L Diedrich; C L Schnaitman; P Reeves
Journal: J Bacteriol Date: 1977-08 Impact factor: 3.490

3. Regulation of outer membrane protein synthesis in Escherichia coli K-12: deletion of ompC affects expression of the OmpF protein.

Authors: C A Schnaitman; G A McDonald
Journal: J Bacteriol Date: 1984-08 Impact factor: 3.490

4. Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase.

Authors: M Gellert; M H O'Dea; T Itoh; J Tomizawa
Journal: Proc Natl Acad Sci U S A Date: 1976-12 Impact factor: 11.205

Review 5. DNA topoisomerases.

Authors: M Gellert
Journal: Annu Rev Biochem Date: 1981 Impact factor: 23.643

6. Promoter exchange between ompF and ompC, genes for osmoregulated major outer membrane proteins of Escherichia coli K-12.

Authors: S Matsuyama; K Inokuchi; S Mizushima
Journal: J Bacteriol Date: 1984-06 Impact factor: 3.490

7. Gene envY of Escherichia coli K-12 affects thermoregulation of major porin expression.

Authors: M D Lundrigan; C F Earhart
Journal: J Bacteriol Date: 1984-01 Impact factor: 3.490

8. Studies on the mode of action of nalidixic acid.

Authors: A M Pedrini; D Geroldi; A Siccardi; A Falaschi
Journal: Eur J Biochem Date: 1972-02-15

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Authors: R E Moses; C C Richardson
Journal: Proc Natl Acad Sci U S A Date: 1970-10 Impact factor: 11.205

10. Porin channels in Escherichia coli: studies with beta-lactams in intact cells.

Authors: H Nikaido; E Y Rosenberg; J Foulds
Journal: J Bacteriol Date: 1983-01 Impact factor: 3.490

9 in total

1. Escherichia coli resistant to cephalosporins and quinolones is still susceptible to the cephalosporin-quinolone ester Ro 23-9424.

Authors: J Pace; A Bertasso; N H Georgopapadakou
Journal: Antimicrob Agents Chemother Date: 1991-05 Impact factor: 5.191

2. Characterization of clinical isolates of Escherichia coli showing high levels of fluoroquinolone resistance.

Authors: N Lehn; J Stower-Hoffmann; T Kott; C Strassner; H Wagner; M Kronke; W Schneider-Brachert
Journal: J Clin Microbiol Date: 1996-03 Impact factor: 5.948

3. Low-level resistance to the cephalosporin 3'-quinolone ester Ro 23-9424 in Escherichia coli.

Authors: J S Chapman; A Bertasso; L M Cummings; N H Georgopapadakou
Journal: Antimicrob Agents Chemother Date: 1995-02 Impact factor: 5.191

4. In vitro activity of amifloxacin against outer membrane mutants of the family Enterobacteriaceae and frequency of spontaneous resistance.

Authors: M Watanabe; M Inoue; S Mitsuhashi
Journal: Antimicrob Agents Chemother Date: 1989-11 Impact factor: 5.191

Review 5. Mechanisms of resistance to quinolones.

Authors: E Cambau; L Gutmann
Journal: Drugs Date: 1993 Impact factor: 9.546

Review 6. Mechanisms of quinolone resistance.

Authors: B Wiedemann; P Heisig
Journal: Infection Date: 1994 Impact factor: 3.553