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Literature DB >> 2541437

The Tc2 transposon in Caenorhabditis elegans.

Abstract

A second family of transposons, named Tc2 elements, has been identified in the nematode Caenorhabditis elegans. Tc2 elements are polymorphic in sequence and are present in different numbers in different strains. Like the transposon Tc1, Tc2 is active in the germ line of some C. elegans strains. A high rate of transposition has been observed in the progeny of certain interstrain crosses, where transposition events are frequent enough to be detected in blot hybridization experiments, without the use of a genetic screen. Our data suggest that transposition of Tc1 and Tc2 may be regulated by the same genomic factors.

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Year: 1989 PMID： 2541437 PMCID： PMC287104 DOI： 10.1073/pnas.86.9.3232

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

20 in total

1. The significance of responses of the genome to challenge.

Authors: B McClintock
Journal: Science Date: 1984-11-16 Impact factor: 47.728

2. Chromosome organization and genic expression.

Authors: B McCLINTOCK
Journal: Cold Spring Harb Symp Quant Biol Date: 1951

3. Analysis of a mutator activity necessary for germline transposition and excision of Tc1 transposable elements in Caenorhabditis elegans.

Authors: I Mori; D G Moerman; R H Waterston
Journal: Genetics Date: 1988-10 Impact factor: 4.562

The Tc2 transposon in Caenorhabditis elegans.

1. The significance of responses of the genome to challenge.

2. Chromosome organization and genic expression.

3. Analysis of a mutator activity necessary for germline transposition and excision of Tc1 transposable elements in Caenorhabditis elegans.

4. Tc1(Hin): a form of the transposable element Tc1 in Caenorhabditis elegans.

5. Analysis of a transposable element in Caenorhabditis elegans.

6. Activation of a transposable element in the germ line but not the soma of Caenorhabditis elegans.

7. Transposition of Tc1 in the nematode Caenorhabditis elegans.

8. Molecular cloning of the muscle gene unc-22 in Caenorhabditis elegans by Tc1 transposon tagging.

9. Evidence for a transposon in Caenorhabditis elegans.

10. The molecular basis of P-M hybrid dysgenesis: the nature of induced mutations.

1. Analysis of the Caenorhabditis elegans axonal guidance and outgrowth gene unc-33.

2. A transposon-related palindromic repetitive sequence from C. elegans.

3. Tec2, a second transposon-like element demonstrating developmentally programmed excision in Euplotes crassus.

Review 4. Forward and reverse mutagenesis in C. elegans.

5. A transposon-based strategy for sequencing repetitive DNA in eukaryotic genomes.

6. Tc4, a Caenorhabditis elegans transposable element with an unusual fold-back structure.

7. Identification of a mariner-like repetitive sequence in C. elegans.

8. Genomic sequence of a mutant strain of Caenorhabditis elegans with an altered recombination pattern.

9. DNA transposons: nature and applications in genomics.

10. The Tc5 family of transposable elements in Caenorhabditis elegans.