Literature DB >> 2541409

Kinetics of exchangeable protons in Z DNA: a UV resonance Raman study.

A Laigle1, L Chinsky, P Y Turpin, B Jollès.   

Abstract

We have studied the hydrogen-deuterium exchange kinetics of the exchangeable protons of the poly(dG-dC).poly(dG-dC) in the Z form of the polymer, using resonance Raman spectroscopy with 257 nm and 284 nm excitation wavelengths. In our experimental conditions (4.5 M NaCl, phosphate buffer pH7, 2 degrees C) the two amino protons and the imino proton of guanine are exchanged with the same exchange half-time of 13 min, whereas the two amino protons of cytosine are exchanged with the same exchange half-time of 51 min.

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Year:  1989        PMID: 2541409      PMCID: PMC317638          DOI: 10.1093/nar/17.7.2493

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  18 in total

1.  Unusual proton exchange properties of Z-form poly[d(G-C)].

Authors:  P A Mirau; D R Kearns
Journal:  Proc Natl Acad Sci U S A       Date:  1985-03       Impact factor: 11.205

2.  Open states in native polynucleotides. II. Hydrogen-exchange study of cytosine-containing double helices.

Authors:  H Teitelbaum; S W Englander
Journal:  J Mol Biol       Date:  1975-02-15       Impact factor: 5.469

3.  Proton exchange and base-pair lifetimes in a deoxy-duplex containing a purine-pyrimidine step and in the duplex of inverse sequence.

Authors:  M Kochoyan; J L Leroy; M Guéron
Journal:  J Mol Biol       Date:  1987-08-05       Impact factor: 5.469

4.  Ultraviolet resonance Raman excitation profiles of nucleic acid bases with excitation from 200 to 300 nanometers.

Authors:  W L Kubasek; B Hudson; W L Peticolas
Journal:  Proc Natl Acad Sci U S A       Date:  1985-04       Impact factor: 11.205

5.  Interbase vibrational coupling in G:C polynucleotide helices.

Authors:  F B Howard; J Frazier; H T Miles
Journal:  Proc Natl Acad Sci U S A       Date:  1969-10       Impact factor: 11.205

6.  Internal motions in B- and Z-form poly(dG-dC).poly(dG-dC): 1H NMR relaxation studies.

Authors:  P A Mirau; R W Behling; D R Kearns
Journal:  Biochemistry       Date:  1985-10-22       Impact factor: 3.162

7.  Internal motions of transfer RNA: a study of exchanging protons by magnetic resonance.

Authors:  J L Leroy; N Bolo; N Figueroa; P Plateau; M Guérón
Journal:  J Biomol Struct Dyn       Date:  1985-02

8.  Recognition of base pairs by polar peptides in double stranded DNA.

Authors:  A Laigle; L Chinsky; P Y Turpin
Journal:  Nucleic Acids Res       Date:  1982-03-11       Impact factor: 16.971

9.  Comparison of poly(dG-dC).poly(dG-dC) conformations in oriented films and in solution.

Authors:  J Pilet; M Leng
Journal:  Proc Natl Acad Sci U S A       Date:  1982-01       Impact factor: 11.205

10.  Conformational changes of poly(dG-dC) . poly(dG-dC) modified by the carcinogen N-acetoxy-N-acetyl-2-aminofluorene.

Authors:  E Sage; M Leng
Journal:  Nucleic Acids Res       Date:  1981-03-11       Impact factor: 16.971

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