Literature DB >> 25406835

A time-resolved luminescence biosensor assay for anaplastic lymphoma kinase (ALK) activity.

Wei Cui1, Laurie L Parker.   

Abstract

A novel time-resolved luminescence biosensor assay for anaplastic lymphoma kinase (ALK) was developed. We used a straightforward strategy to modify a known ALK substrate into a peptide biosensor that can accommodate terbium luminescence sensitization upon its phosphorylation by ALK. Since this strategy is generalizable, this high-throughput screening compatible assay serves as an example for development of other kinase assays that employ terbium luminescence as a read-out.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 25406835      PMCID： PMC4288484          DOI： 10.1039/c4cc07453j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  23 in total

1.  A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays.

Authors: 
Journal:  J Biomol Screen       Date:  1999

2.  Enzymatic characterization of c-Met receptor tyrosine kinase oncogenic mutants and kinetic studies with aminopyridine and triazolopyrazine inhibitors.

Authors:  Sergei L Timofeevski; Michele A McTigue; Kevin Ryan; Jean Cui; Helen Y Zou; Jeff X Zhu; Fannie Chau; Gordon Alton; Shannon Karlicek; James G Christensen; Brion W Murray
Journal:  Biochemistry       Date:  2009-06-16       Impact factor: 3.162

3.  Detection of phosphorylation states by intermolecular sensitization of lanthanide-peptide conjugates.

Authors:  Elena Pazos; Marko Goličnik; José L Mascareñas; M Eugenio Vázquez
Journal:  Chem Commun (Camb)       Date:  2012-10-04       Impact factor: 6.222

Review 4.  Lanthanide luminescence for biomedical analyses and imaging.

Authors:  Jean-Claude G Bünzli
Journal:  Chem Rev       Date:  2010-05-12       Impact factor: 60.622

5.  Unique substrate specificity of anaplastic lymphoma kinase (ALK): development of phosphoacceptor peptides for the assay of ALK activity.

Authors:  Arianna Donella-Deana; Oriano Marin; Luca Cesaro; Rosalind H Gunby; Anna Ferrarese; Addolorata M L Coluccia; Carmen J Tartari; Luca Mologni; Leonardo Scapozza; Carlo Gambacorti-Passerini; Lorenzo A Pinna
Journal:  Biochemistry       Date:  2005-06-14       Impact factor: 3.162

Review 6.  Anaplastic Lymphoma Kinase: role in specific tumours, and development of small molecule inhibitors for cancer therapy.

Authors:  E Ardini; P Magnaghi; P Orsini; A Galvani; M Menichincheri
Journal:  Cancer Lett       Date:  2010-10-08       Impact factor: 8.679

7.  Escaping ALK inhibition: mechanisms of and strategies to overcome resistance.

Authors:  Christine M Lovly; William Pao
Journal:  Sci Transl Med       Date:  2012-02-08       Impact factor: 17.956

8.  Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.

Authors:  Christian C Lee; Yong Jia; Nanxin Li; Xiuying Sun; Kenneth Ng; Eileen Ambing; Mu-Yun Gao; Su Hua; Connie Chen; Sungjoon Kim; Pierre-Yves Michellys; Scott A Lesley; Jennifer L Harris; Glen Spraggon
Journal:  Biochem J       Date:  2010-09-15       Impact factor: 3.857

9.  ROS1 and ALK fusions in colorectal cancer, with evidence of intratumoral heterogeneity for molecular drivers.

Authors:  Dara L Aisner; Teresa T Nguyen; Diego D Paskulin; Anh T Le; Jerry Haney; Nathan Schulte; Fiona Chionh; Jenny Hardingham; John Mariadason; Niall Tebbutt; Robert C Doebele; Andrew J Weickhardt; Marileila Varella-Garcia
Journal:  Mol Cancer Res       Date:  2013-12-02       Impact factor: 5.852

10.  A luminescent sensor for tyrosine phosphorylation.

Authors:  Matthew S Tremblay; Minhee Lee; Dalibor Sames
Journal:  Org Lett       Date:  2007-12-11       Impact factor: 6.005
View more
  9 in total

1.  Redox-Responsive Protein Design: Design of a Small Protein Motif Dependent on Glutathionylation.

Authors:  Michael J Scheuermann; Christina R Forbes; Neal J Zondlo
Journal:  Biochemistry       Date:  2018-12-13       Impact factor: 3.162

2.  Phosphorylation-dependent protein design: design of a minimal protein kinase-inducible domain.

Authors:  Feng Gao; Blair S Thornley; Caitlin M Tressler; Devan Naduthambi; Neal J Zondlo
Journal:  Org Biomol Chem       Date:  2019-04-17       Impact factor: 3.876

3.  High-throughput Identification of FLT3 Wild-type and Mutant Kinase Substrate Preferences and Application to Design of Sensitive In Vitro Kinase Assay Substrates.

Authors:  Minervo Perez; John Blankenhorn; Kevin J Murray; Laurie L Parker
Journal:  Mol Cell Proteomics       Date:  2018-12-12       Impact factor: 5.911

4.  Multicolored, Tb³⁺-Based Antibody-Free Detection of Multiple Tyrosine Kinase Activities.

Authors:  Andrew M Lipchik; Minervo Perez; Wei Cui; Laurie L Parker
Journal:  Anal Chem       Date:  2015-07-24       Impact factor: 6.986

5.  A Cell-Based Assay for Measuring Endogenous BcrAbl Kinase Activity and Inhibitor Resistance.

Authors:  Steven B Ouellette; Brett M Noel; Laurie L Parker
Journal:  PLoS One       Date:  2016-09-06       Impact factor: 3.240

6.  Fungal F8-Culture Filtrate Induces Tomato Resistance against Tomato Yellow Leaf Curl Thailand Virus.

Authors:  Yi-Shu Chiu; Yuh Tzean; Yi-Hui Chen; Chi-Wei Tsai; Hsin-Hung Yeh
Journal:  Viruses       Date:  2021-07-23       Impact factor: 5.048

7.  Coupling the folding of a β-hairpin with chelation-enhanced luminescence of Tb(III) and Eu(III) ions for specific sensing of a viral RNA.

Authors:  Cristina Penas; José L Mascareñas; M Eugenio Vázquez
Journal:  Chem Sci       Date:  2016-04-01       Impact factor: 9.825

Review 8.  Selective Sensing of Tyrosine Phosphorylation in Peptides Using Terbium(III) Complexes.

Authors:  Jun Sumaoka; Hiroki Akiba; Makoto Komiyama
Journal:  Int J Anal Chem       Date:  2016-06-08       Impact factor: 1.885

9.  Modular, Antibody-free Time-Resolved LRET Kinase Assay Enabled by Quantum Dots and Tb(3+)-sensitizing Peptides.

Authors:  Wei Cui; Laurie L Parker
Journal:  Sci Rep       Date:  2016-07-18       Impact factor: 4.379
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.