| Literature DB >> 18069839 |
Matthew S Tremblay1, Minhee Lee, Dalibor Sames.
Abstract
We have developed a luminogenic probe for tyrosine phosphorylation based on a short peptide sequence containing an iminodiacetate moiety near the site of phosphorylation. In response to kinase activity, the probe provides a strong luminescence enhancement, resulting from the increased ability of the probe to bind and sensitize Tb3+ and Eu3+ ions upon phosphorylation.Entities:
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Year: 2007 PMID: 18069839 DOI: 10.1021/ol701920x
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005