Literature DB >> 25403659

In vivo selection of Plasmodium falciparum Pfcrt and Pfmdr1 variants by artemether-lumefantrine and dihydroartemisinin-piperaquine in Burkina Faso.

Vito Baraka1, Halidou Tinto2, Innocent Valea2, Robert Fitzhenry3, Christopher Delgado-Ratto4, Martin K Mbonye5, Chantal Van Overmeir3, Anna Rosanas-Urgell3, Jean-Pierre Van Geertruyden4, Umberto D'Alessandro6, Annette Erhart3.   

Abstract

Plasmodium falciparum Pfcrt-76 and Pfmdr1-86 gene polymorphisms were determined during a clinical trial in Burkina Faso comparing the efficacies of dihydroartemisinin-piperaquine (DHA-PPQ) and artemether-lumefantrine (AL). Significant selection of Pfcrt-K76 was observed after exposure to AL and DHA-PPQ, as well as selection of Pfmdr1-N86 after AL but not DHA-PPQ treatment, suggesting reverse selection on the Pfcrt gene by PPQ. These results support the rational use of DHA-PPQ in settings where chloroquine (CQ) resistance is high.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2014        PMID： 25403659      PMCID： PMC4291431          DOI： 10.1128/AAC.03647-14

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  21 in total

1.  Selection of Plasmodium falciparum pfmdr1 alleles following therapy with artemether-lumefantrine in an area of Uganda where malaria is highly endemic.

Authors:  Christian Dokomajilar; Samuel L Nsobya; Bryan Greenhouse; Philip J Rosenthal; Grant Dorsey
Journal:  Antimicrob Agents Chemother       Date:  2006-05       Impact factor: 5.191

2.  Piperaquine resistance is associated with a copy number variation on chromosome 5 in drug-pressured Plasmodium falciparum parasites.

Authors:  Richard T Eastman; Neekesh V Dharia; Elizabeth A Winzeler; David A Fidock
Journal:  Antimicrob Agents Chemother       Date:  2011-05-16       Impact factor: 5.191

3.  Comparative impacts over 5 years of artemisinin-based combination therapies on Plasmodium falciparum polymorphisms that modulate drug sensitivity in Ugandan children.

Authors:  Melissa D Conrad; Norbert LeClair; Emmanuel Arinaitwe; Humphrey Wanzira; Abel Kakuru; Victor Bigira; Mary Muhindo; Moses R Kamya; Jordan W Tappero; Bryan Greenhouse; Grant Dorsey; Philip J Rosenthal
Journal:  J Infect Dis       Date:  2014-03-08       Impact factor: 5.226

4.  Absence of association between piperaquine in vitro responses and polymorphisms in the pfcrt, pfmdr1, pfmrp, and pfnhe genes in Plasmodium falciparum.

Authors:  Sébastien Briolant; Maud Henry; Claude Oeuvray; Rémy Amalvict; Eric Baret; Eric Didillon; Christophe Rogier; Bruno Pradines
Journal:  Antimicrob Agents Chemother       Date:  2010-06-14       Impact factor: 5.191

5.  Selection of known Plasmodium falciparum resistance-mediating polymorphisms by artemether-lumefantrine and amodiaquine-sulfadoxine-pyrimethamine but not dihydroartemisinin-piperaquine in Burkina Faso.

Authors:  Anyirékun Fabrice Somé; Yves Y Séré; Christian Dokomajilar; Issaka Zongo; Noël Rouamba; Bryan Greenhouse; Jean-Bosco Ouédraogo; Philip J Rosenthal
Journal:  Antimicrob Agents Chemother       Date:  2010-03-15       Impact factor: 5.191

6.  In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1.

Authors:  Leah Mwai; Steven M Kiara; Abdi Abdirahman; Lewa Pole; Anja Rippert; Abdi Diriye; Pete Bull; Kevin Marsh; Steffen Borrmann; Alexis Nzila
Journal:  Antimicrob Agents Chemother       Date:  2009-09-21       Impact factor: 5.191

7.  In vitro sensitivities of Plasmodium falciparum to different antimalarial drugs in Uganda.

Authors:  Samuel L Nsobya; Moses Kiggundu; Sarah Nanyunja; Moses Joloba; Bryan Greenhouse; Philip J Rosenthal
Journal:  Antimicrob Agents Chemother       Date:  2010-01-11       Impact factor: 5.191

8.  Selection of pfmdr1 and pfcrt alleles in amodiaquine treatment failure in north-western Burkina Faso.

Authors:  Ina Danquah; Boubacar Coulibaly; Peter Meissner; Inga Petruschke; Olaf Müller; Frank P Mockenhaupt
Journal:  Acta Trop       Date:  2010-01-07       Impact factor: 3.112

9.  Selection of drug resistance-mediating Plasmodium falciparum genetic polymorphisms by seasonal malaria chemoprevention in Burkina Faso.

Authors:  Anyirékun Fabrice Somé; Issaka Zongo; Yves-Daniel Compaoré; Souleymane Sakandé; François Nosten; Jean-Bosco Ouédraogo; Philip J Rosenthal
Journal:  Antimicrob Agents Chemother       Date:  2014-04-14       Impact factor: 5.191

10.  Dihydroartemisinin-piperaquine and artemether-lumefantrine for treating uncomplicated malaria in African children: a randomised, non-inferiority trial.

Authors:  Quique Bassat; Modest Mulenga; Halidou Tinto; Patrice Piola; Steffen Borrmann; Clara Menéndez; Michael Nambozi; Innocent Valéa; Carolyn Nabasumba; Philip Sasi; Antonella Bacchieri; Marco Corsi; David Ubben; Ambrose Talisuna; Umberto D'Alessandro
Journal:  PLoS One       Date:  2009-11-17       Impact factor: 3.240
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  18 in total

1.  Antimalarial Drug Resistance Profiling of Plasmodium falciparum Infections in Ghana Using Molecular Inversion Probes and Next-Generation Sequencing.

Authors:  Benedicta A Mensah; Ozkan Aydemir; James L Myers-Hansen; Millicent Opoku; Nicholas J Hathaway; Patrick W Marsh; Francis Anto; Jeffrey Bailey; Benjamin Abuaku; Anita Ghansah
Journal:  Antimicrob Agents Chemother       Date:  2020-03-24       Impact factor: 5.191

2.  Impact of Intermittent Preventive Treatment During Pregnancy on Plasmodium falciparum Drug Resistance-Mediating Polymorphisms in Uganda.

Authors:  Melissa D Conrad; Daniel Mota; Marissa Foster; Stephen Tukwasibwe; Jennifer Legac; Patrick Tumwebaze; Meghan Whalen; Abel Kakuru; Patience Nayebare; Erika Wallender; Diane V Havlir; Prasanna Jagannathan; Liusheng Huang; Francesca Aweeka; Moses R Kamya; Grant Dorsey; Philip J Rosenthal
Journal:  J Infect Dis       Date:  2017-11-15       Impact factor: 5.226

3.  Associations between Aminoquinoline Resistance Genotypes and Clinical Presentations of Plasmodium falciparum Infection in Uganda.

Authors:  Gloria Cuu; Victor Asua; Stephen Tukwasibwe; Sam L Nsobya; Ann Nanteza; Magambo Phillip Kimuda; Arthur Mpimbaza; Philip J Rosenthal
Journal:  Antimicrob Agents Chemother       Date:  2020-09-21       Impact factor: 5.191

4.  Polymorphisms in K13, pfcrt, pfmdr1, pfdhfr, and pfdhps in parasites isolated from symptomatic malaria patients in Burkina Faso.

Authors:  Anyirékun Fabrice Somé; Hermann Sorgho; Issaka Zongo; Thomas Bazié; Frédéric Nikiéma; Amadé Sawadogo; Moussa Zongo; Yves-Daniel Compaoré; Jean-Bosco Ouédraogo
Journal:  Parasite       Date:  2016-12-22       Impact factor: 3.000

5.  Reduced ex vivo susceptibility of Plasmodium falciparum after oral artemether-lumefantrine treatment in Mali.

Authors:  Souleymane Dama; Hamidou Niangaly; Amed Ouattara; Issaka Sagara; Sekou Sissoko; Oumar Bila Traore; Amadou Bamadio; Niawanlou Dara; Moussa Djimde; Mohamed Lamine Alhousseini; Siaka Goita; Hamma Maiga; Antoine Dara; Ogobara K Doumbo; Abdoulaye A Djimde
Journal:  Malar J       Date:  2017-02-02       Impact factor: 2.979

6.  Randomised controlled trial of two sequential artemisinin-based combination therapy regimens to treat uncomplicated falciparum malaria in African children: a protocol to investigate safety, efficacy and adherence.

Authors:  Henk Dfh Schallig; Halidou Tinto; Patrick Sawa; Harparkash Kaur; Stephan Duparc; Deus S Ishengoma; Pascal Magnussen; Michael Alifrangis; Colin J Sutherland
Journal:  BMJ Glob Health       Date:  2017-08-30

7.  Identification of large variation in pfcrt, pfmdr-1 and pfubp-1 markers in Plasmodium falciparum isolates from Ethiopia and Tanzania.

Authors:  Lemu Golassa; Erasmus Kamugisha; Deus S Ishengoma; Vito Baraka; Alex Shayo; Frederick N Baliraine; Nizar Enweji; Berhanu Erko; Abraham Aseffa; Angel Choy; Göte Swedberg
Journal:  Malar J       Date:  2015-07-08       Impact factor: 2.979

8.  PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers.

Authors:  Richard T Eastman; Pwint Khine; Ruili Huang; Craig J Thomas; Xin-Zhuan Su
Journal:  Sci Rep       Date:  2016-05-05       Impact factor: 4.379

9.  Artesunate-Amodiaquine and Artemether-Lumefantrine Therapies and Selection of Pfcrt and Pfmdr1 Alleles in Nanoro, Burkina Faso.

Authors:  Paul Sondo; Karim Derra; Seydou Diallo Nakanabo; Zekiba Tarnagda; Adama Kazienga; Odile Zampa; Innocent Valéa; Hermann Sorgho; Ellis Owusu-Dabo; Jean-Bosco Ouédraogo; Tinga Robert Guiguemdé; Halidou Tinto
Journal:  PLoS One       Date:  2016-03-31       Impact factor: 3.240

10.  Assessment of pharmacokinetic compatibility of short acting CDRI candidate trioxane derivative, 99-411, with long acting prescription antimalarials, lumefantrine and piperaquine.

Authors:  Isha Taneja; Kanumuri Siva Rama Raju; Sheelendra Pratap Singh; Muhammad Wahajuddin
Journal:  Sci Rep       Date:  2015-11-25       Impact factor: 4.379
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