Literature DB >> 25401005

Comprehensive spectral endoscopy of topically applied SERS nanoparticles in the rat esophagus.

Yu W Wang1, Altaz Khan2, Steven Y Leigh3, Danni Wang3, Ye Chen4, Daphne Meza3, Jonathan T C Liu4.   

Abstract

The early detection and biological investigation of esophageal cancer would benefit from the development of advanced imaging techniques to screen for the molecular changes that precede and accompany the onset of cancer. Surface-enhanced Raman scattering (SERS) nanoparticles (NPs) have the potential to improve cancer detection and the investigation of cancer progression through the sensitive and multiplexed phenotyping of cell-surface biomarkers. Here, a miniature endoscope featuring rotational scanning and axial pull back has been developed for 2D spectral imaging of SERS NPs topically applied on the lumenal surface of the rat esophagus. Raman signals from low-pM concentrations of SERS NP mixtures are demultiplexed in real time to accurately calculate the concentration and ratio of the NPs. Ex vivo and in vivo experiments demonstrate the feasibility of topical application and imaging of multiplexed SERS NPs along the entire length of the rat esophagus.

Entities:  

Keywords:  (110.2350) Fiber optics imaging; (160.4236) Nanomaterials; (170.0170) Medical optics and biotechnology; (170.2150) Endoscopic imaging; (170.2680) Gastrointestinal; (170.5660) Raman spectroscopy

Year:  2014        PMID： 25401005      PMCID： PMC4230873          DOI： 10.1364/BOE.5.002883

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN： 2156-7085            Impact factor:   3.732


  41 in total

1.  Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells.

Authors:  B Devika Chithrani; Arezou A Ghazani; Warren C W Chan
Journal:  Nano Lett       Date:  2006-04       Impact factor: 11.189

2.  Composite organic-inorganic nanoparticles (COINs) with chemically encoded optical signatures.

Authors:  Xing Su; Jingwu Zhang; Lei Sun; Tae-Woong Koo; Selena Chan; Narayan Sundararajan; Mineo Yamakawa; Andrew A Berlin
Journal:  Nano Lett       Date:  2005-01       Impact factor: 11.189

3.  A Raman-based endoscopic strategy for multiplexed molecular imaging.

Authors:  Cristina L Zavaleta; Ellis Garai; Jonathan T C Liu; Steven Sensarn; Michael J Mandella; Dominique Van de Sompel; Shai Friedland; Jacques Van Dam; Christopher H Contag; Sanjiv S Gambhir
Journal:  Proc Natl Acad Sci U S A       Date:  2013-05-23       Impact factor: 11.205

4.  High-sensitivity, real-time, ratiometric imaging of surface-enhanced Raman scattering nanoparticles with a clinically translatable Raman endoscope device.

Authors:  Ellis Garai; Steven Sensarn; Cristina L Zavaleta; Dominique Van de Sompel; Nathan O Loewke; Michael J Mandella; Sanjiv S Gambhir; Christopher H Contag
Journal:  J Biomed Opt       Date:  2013-09       Impact factor: 3.170

5.  Improved tumor contrast achieved by single time point dual-reporter fluorescence imaging.

Authors:  Kenneth M Tichauer; Kimberley S Samkoe; Kristian J Sexton; Jason R Gunn; Tayyaba Hasan; Brian W Pogue
Journal:  J Biomed Opt       Date:  2012-06       Impact factor: 3.170

6.  Rapid ratiometric biomarker detection with topically applied SERS nanoparticles.

Authors:  Yu Winston Wang; Altaz Khan; Madhura Som; Danni Wang; Ye Chen; Steven Y Leigh; Daphne Meza; Patrick Z McVeigh; Brian C Wilson; Jonathan T C Liu
Journal:  Technology (Singap World Sci)       Date:  2014-06-01

Review 7.  Peptide phage display: opportunities for development of personalized anti-cancer strategies.

Authors:  T I Samoylova; N E Morrison; L P Globa; N R Cox
Journal:  Anticancer Agents Med Chem       Date:  2006-01       Impact factor: 2.505

8.  Functional imaging of colonic mucosa with a fibered confocal microscope for real-time in vivo pathology.

Authors:  Thomas D Wang; Shai Friedland; Peyman Sahbaie; Roy Soetikno; Pei-Lin Hsiung; Jonathan T C Liu; James M Crawford; Christopher H Contag
Journal:  Clin Gastroenterol Hepatol       Date:  2007-10-23       Impact factor: 11.382

9.  A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle.

Authors:  Moritz F Kircher; Adam de la Zerda; Jesse V Jokerst; Cristina L Zavaleta; Paul J Kempen; Erik Mittra; Ken Pitter; Ruimin Huang; Carl Campos; Frezghi Habte; Robert Sinclair; Cameron W Brennan; Ingo K Mellinghoff; Eric C Holland; Sanjiv S Gambhir
Journal:  Nat Med       Date:  2012-04-15       Impact factor: 53.440

10.  Method for assessing the reliability of molecular diagnostics based on multiplexed SERS-coded nanoparticles.

Authors:  Steven Y Leigh; Madhura Som; Jonathan T C Liu
Journal:  PLoS One       Date:  2013-04-19       Impact factor: 3.240
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  14 in total

1.  Raman-Encoded Molecular Imaging with Topically Applied SERS Nanoparticles for Intraoperative Guidance of Lumpectomy.

Authors:  Yu Winston Wang; Nicholas P Reder; Soyoung Kang; Adam K Glaser; Qian Yang; Matthew A Wall; Sara H Javid; Suzanne M Dintzis; Jonathan T C Liu
Journal:  Cancer Res       Date:  2017-06-14       Impact factor: 12.701

2.  Multimodal assessment of SERS nanoparticle biodistribution post ingestion reveals new potential for clinical translation of Raman imaging.

Authors:  Jos L Campbell; Elliott D SoRelle; Ohad Ilovich; Orly Liba; Michelle L James; Zhen Qiu; Valerie Perez; Carmel T Chan; Adam de la Zerda; Cristina Zavaleta
Journal:  Biomaterials       Date:  2017-04-28       Impact factor: 12.479

3.  Microscopic investigation of" topically applied nanoparticles for molecular imaging of fresh tissue surfaces.

Authors:  Soyoung Kang; Yu Winston Wang; Xiaochun Xu; Eric Navarro; Kenneth M Tichauer; Jonathan T C Liu
Journal:  J Biophotonics       Date:  2018-01-29       Impact factor: 3.207

Review 4.  Quantitative in vivo cell-surface receptor imaging in oncology: kinetic modeling and paired-agent principles from nuclear medicine and optical imaging.

Authors:  Kenneth M Tichauer; Yu Wang; Brian W Pogue; Jonathan T C Liu
Journal:  Phys Med Biol       Date:  2015-07-02       Impact factor: 3.609

5.  Rinsing paired-agent model (RPAM) to quantify cell-surface receptor concentrations in topical staining applications of thick tissues.

Authors:  Xiaochun Xu; Yu Wang; Jialing Xiang; Jonathan T C Liu; Kenneth M Tichauer
Journal:  Phys Med Biol       Date:  2017-05-26       Impact factor: 3.609

6.  Multiplexed Molecular Imaging of Fresh Tissue Surfaces Enabled by Convection-Enhanced Topical Staining with SERS-Coded Nanoparticles.

Authors:  Yu W Wang; Josh D Doerksen; Soyoung Kang; Daniel Walsh; Qian Yang; Daniel Hong; Jonathan T C Liu
Journal:  Small       Date:  2016-08-29       Impact factor: 13.281

7.  Surgical Guidance via Multiplexed Molecular Imaging of Fresh Tissues Labeled with SERS-Coded Nanoparticles.

Authors:  Yu Wang; Soyoung Kang; Josh D Doerksen; Adam K Glaser; Jonathan T C Liu
Journal:  IEEE J Sel Top Quantum Electron       Date:  2016-03-21       Impact factor: 4.544

8.  In vivo multiplexed molecular imaging of esophageal cancer via spectral endoscopy of topically applied SERS nanoparticles.

Authors:  Yu Winston Wang; Soyoung Kang; Altaz Khan; Philip Q Bao; Jonathan T C Liu
Journal:  Biomed Opt Express       Date:  2015-09-01       Impact factor: 3.732

9.  Endoscopic sensing of alveolar pH.

Authors:  D Choudhury; M G Tanner; S McAughtrie; F Yu; B Mills; T R Choudhary; S Seth; T H Craven; J M Stone; I K Mati; C J Campbell; M Bradley; C K I Williams; K Dhaliwal; T A Birks; R R Thomson
Journal:  Biomed Opt Express       Date:  2016-12-13       Impact factor: 3.732

10.  Quantification of the binding potential of cell-surface receptors in fresh excised specimens via dual-probe modeling of SERS nanoparticles.

Authors:  Lagnojita Sinha; Yu Wang; Cynthia Yang; Altaz Khan; Jovan G Brankov; Jonathan T C Liu; Kenneth M Tichauer
Journal:  Sci Rep       Date:  2015-02-26       Impact factor: 4.379
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