Ke Chen1, Yu Pan1, Jia-Qin Cai1, Xiao-Wu Xu1, Di Wu1, Yi-Ping Mou1. 1. Ke Chen, Yu Pan, Jia-Qin Cai, Xiao-Wu Xu, Di Wu, Yi-Ping Mou, Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, China.
Abstract
AIM: To systematically review the surgical outcomes of totally laparoscopic gastrectomy (TLG) vs open gastrectomy (OG) for gastric cancer. METHODS: A systematic search of PubMed, Embase, Cochrane Library, and Web of Science was conducted. All original studies comparing TLG with OG were included for critical appraisal. Data synthesis and statistical analysis were carried out using RevMan 5.1 software. RESULTS: One RCT and 13 observational studies involving 1532 patients were included (721 TLG and 811 OG). TLG was associated with longer operation time [weighted mean difference (WMD) = 58.04 min, 95%CI: 37.77-78.32, P < 0.001], less blood loss [WMD = -167.57 min, 95%CI: -208.79-(-126.34), P < 0.001], shorter hospital stay [WMD = -3.75 d, 95%CI: -4.88-(-2.63), P < 0.001] and fewer postoperative complications (RR = 0.71, 95%CI: 0.58-0.86, P < 0.001). The number of harvested lymph nodes, surgical margin, mortality and cancer recurrence rate were similar between the two groups. CONCLUSION: TLG may be a technically safe, feasible and favorable approach in terms of better cosmesis, less blood loss and faster recovery compared with OG.
AIM: To systematically review the surgical outcomes of totally laparoscopic gastrectomy (TLG) vs open gastrectomy (OG) for gastric cancer. METHODS: A systematic search of PubMed, Embase, Cochrane Library, and Web of Science was conducted. All original studies comparing TLG with OG were included for critical appraisal. Data synthesis and statistical analysis were carried out using RevMan 5.1 software. RESULTS: One RCT and 13 observational studies involving 1532 patients were included (721 TLG and 811 OG). TLG was associated with longer operation time [weighted mean difference (WMD) = 58.04 min, 95%CI: 37.77-78.32, P < 0.001], less blood loss [WMD = -167.57 min, 95%CI: -208.79-(-126.34), P < 0.001], shorter hospital stay [WMD = -3.75 d, 95%CI: -4.88-(-2.63), P < 0.001] and fewer postoperative complications (RR = 0.71, 95%CI: 0.58-0.86, P < 0.001). The number of harvested lymph nodes, surgical margin, mortality and cancer recurrence rate were similar between the two groups. CONCLUSION:TLG may be a technically safe, feasible and favorable approach in terms of better cosmesis, less blood loss and faster recovery compared with OG.
Authors: Sherief Shawki; Badma Bashankaev; Paula Denoya; Christina Seo; Eric G Weiss; Steven D Wexner Journal: Surg Endosc Date: 2009-03-06 Impact factor: 4.584
Authors: Chang Hak Yoo; Hyung Ook Kim; Sang Il Hwang; Byung Ho Son; Jun Ho Shin; Hungdai Kim Journal: Surg Endosc Date: 2009-01-27 Impact factor: 4.584
Authors: Vivian E Strong; Nicolas Devaud; Peter J Allen; Mithat Gonen; Murray F Brennan; Daniel Coit Journal: Ann Surg Oncol Date: 2009-04-04 Impact factor: 5.344
Authors: Magdalena Pisarska; Michał Pędziwiatr; Piotr Major; Michał Kisielewski; Marcin Migaczewski; Mateusz Rubinkiewicz; Piotr Budzyński; Krzysztof Przęczek; Anna Zub-Pokrowiecka; Andrzej Budzyński Journal: Med Sci Monit Date: 2017-03-23
Authors: Hylke J F Brenkman; Juan Correa-Cote; Jelle P Ruurda; Richard van Hillegersberg Journal: J Gastrointest Surg Date: 2016-08-25 Impact factor: 3.452