Literature DB >> 25399056

Biosynthetic incorporation of the azulene moiety in proteins with high efficiency.

Jinfeng Shao1, Ivan V Korendovych, Jaap Broos.   

Abstract

Biosynthetic incorporation of β-(1-azulenyl)-L-alanine, an isostere of tryptophan, is reported using a tryptophan auxotroph expression host. The azulene moiety introduced this way in proteins features many attractive spectroscopic properties, particularly suitable for in vivo studies.

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Year:  2014        PMID: 25399056     DOI: 10.1007/s00726-014-1870-4

Source DB:  PubMed          Journal:  Amino Acids        ISSN: 0939-4451            Impact factor:   3.520


  7 in total

Review 1.  Minimalist IR and fluorescence probes of protein function.

Authors:  Pallavi M Gosavi; Ivan V Korendovych
Journal:  Curr Opin Chem Biol       Date:  2016-09-10       Impact factor: 8.822

2.  Functional characterization of a melittin analog containing a non-natural tryptophan analog.

Authors:  Zachary Ridgway; Angela L Picciano; Pallavi M Gosavi; Yurii S Moroz; Christopher E Angevine; Amy E Chavis; Joseph E Reiner; Ivan V Korendovych; Gregory A Caputo
Journal:  Biopolymers       Date:  2015-07       Impact factor: 2.505

3.  Site-Specific Interrogation of Protein Structure and Stability.

Authors:  Debopreeti Mukherjee; Ismail A Ahmed; Feng Gai
Journal:  Methods Mol Biol       Date:  2022

4.  Broad substrate tolerance of tubulin tyrosine ligase enables one-step site-specific enzymatic protein labeling.

Authors:  Dominik Schumacher; Oliver Lemke; Jonas Helma; Lena Gerszonowicz; Verena Waller; Tina Stoschek; Patrick M Durkin; Nediljko Budisa; Heinrich Leonhardt; Bettina G Keller; Christian P R Hackenberger
Journal:  Chem Sci       Date:  2017-03-20       Impact factor: 9.825

5.  Versatile Vibrational Energy Sensors for Proteins.

Authors:  Jan G Löffler; Erhan Deniz; Carolin Feid; Valentin G Franz; Jens Bredenbeck
Journal:  Angew Chem Int Ed Engl       Date:  2022-04-06       Impact factor: 16.823

6.  Expanding the Scope of Orthogonal Translation with Pyrrolysyl-tRNA Synthetases Dedicated to Aromatic Amino Acids.

Authors:  Hsueh-Wei Tseng; Tobias Baumann; Huan Sun; Yane-Shih Wang; Zoya Ignatova; Nediljko Budisa
Journal:  Molecules       Date:  2020-09-25       Impact factor: 4.411

7.  Beneficial Impacts of Incorporating the Non-Natural Amino Acid Azulenyl-Alanine into the Trp-Rich Antimicrobial Peptide buCATHL4B.

Authors:  Areetha R D'Souza; Matthew R Necelis; Alona Kulesha; Gregory A Caputo; Olga V Makhlynets
Journal:  Biomolecules       Date:  2021-03-12
  7 in total

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