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Literature DB >> 2539800

Non-A, non-B hepatitis: visualization of virus-like particles from chimpanzee and human sera.

Abstract

Virus-like particles (VLP), morphologically similar to togavirus particles, were detected in the sera of chimpanzees and humans with chronic non-A, non-B (NANB) hepatitis. Particles resembling the virus were also found in the cytoplasm of hepatocytes obtained from NANB hepatitis infected chimpanzees. Furthermore, two chimpanzees inoculated with materials containing the VLP developed NANB hepatitis. These results strongly suggest that the VLP may be closely associated with the agent of NANB hepatitis.

Entities: Disease Species

Mesh：

Year: 1989 PMID： 2539800 DOI： 10.1007/bf01315557

Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574

9 in total

1. Posttransfusion non-A, non-B hepatitis in chimpanzees. Physicochemical evidence that the tubule-forming agent is a small, enveloped virus.

Authors: D W Bradley; K A McCaustland; E H Cook; C A Schable; J W Ebert; J E Maynard
Journal: Gastroenterology Date: 1985-03 Impact factor: 22.682

2. Candidate cause identified of non-A, non-B hepatitis.

Authors: C Ezzell
Journal: Nature Date: 1988-05-19 Impact factor: 49.962

Review 3. Non-A, non-B hepatitis viruses.

Authors: A M Prince
Journal: Annu Rev Microbiol Date: 1983 Impact factor: 15.500

4. Non-A, non-B hepatitis: ultrastructural evidence for two agents in experimentally infected chimpanzees.

Authors: Y K Shimizu; S M Feinstone; R H Purcell; H J Alter; W T London
Journal: Science Date: 1979-07-13 Impact factor: 47.728

5. Experimental infection of chimpanzees with antihemophilic (factor VIII) materials: recovery of virus-like particles associated with non-A, non-B hepatitis.

Authors: D W Bradley; E H Cook; J E Maynard; K A McCaustland; J W Ebert; G H Dolana; R A Petzel; R J Kantor; A Heilbrunn; H A Fields; B L Murphy
Journal: J Med Virol Date: 1979 Impact factor: 2.327

6. Transmissible agent in non-A, non-B hepatitis.

Authors: H J Alter; R H Purcell; P V Holland; H Popper
Journal: Lancet Date: 1978-03-04 Impact factor: 79.321

7. Transmission of non-A, non-B hepatitis from man to chimpanzee.

Authors: E Tabor; R J Gerety; J A Drucker; L B Seeff; J H Hoofnagle; D R Jackson; M April; L F Barker; G Pineda-Tamondong
Journal: Lancet Date: 1978-03-04 Impact factor: 79.321

8. Viruslike particles in a plasma fraction (fibrinogen) and in the circulation of apparently healthy blood donors capable of inducing non-A/non-B hepatitis in humans and chimpanzees.

Authors: H Yoshizawa; Y Akahane; Y Itoh; S Iwakiri; K Kitajima; M Morita; A Tanaka; T Nojiri; M Shimizu; Y Miyakawa; M Mayumi
Journal: Gastroenterology Date: 1980-09 Impact factor: 22.682

9. Detection of reverse transcriptase activity in association with the non-A, non-B hepatitis agent(s).

Authors: B Seto; W G Coleman; S Iwarson; R J Gerety
Journal: Lancet Date: 1984-10-27 Impact factor: 79.321

9 in total

6 in total

Review 6. Hepatitis C virus.

Authors: P G Plagemann
Journal: Arch Virol Date: 1991 Impact factor: 2.574