Literature DB >> 25396343

Systematic analysis of immunodeficiency.

David F Tough1.   

Abstract

Humans deficient in the adaptor MyD88 or the kinase IRAK4 suffer from primary immunodeficiency. Blood cells from these patients show defective induction of specific subsets of genes after exposure to microbial stimuli in vitro.

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Year:  2014        PMID： 25396343     DOI： 10.1038/ni.3029

Source DB:  PubMed          Journal:  Nat Immunol        ISSN： 1529-2908            Impact factor:   25.606


  8 in total

Review 1.  Accessory molecules for Toll-like receptors and their function.

Authors:  Clarissa C Lee; Ana M Avalos; Hidde L Ploegh
Journal:  Nat Rev Immunol       Date:  2012-02-03       Impact factor: 53.106

Review 2.  Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa.

Authors:  Hugo Cruz Ramos; Martin Rumbo; Jean-Claude Sirard
Journal:  Trends Microbiol       Date:  2004-11       Impact factor: 17.079

Review 3.  Assembly and localization of Toll-like receptor signalling complexes.

Authors:  Nicholas J Gay; Martyn F Symmons; Monique Gangloff; Clare E Bryant
Journal:  Nat Rev Immunol       Date:  2014-08       Impact factor: 53.106

Review 4.  What the Myddosome structure tells us about the initiation of innate immunity.

Authors:  Nicholas J Gay; Monique Gangloff; Luke A J O'Neill
Journal:  Trends Immunol       Date:  2011-01-25       Impact factor: 16.687

5.  Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling.

Authors:  Su-Chang Lin; Yu-Chih Lo; Hao Wu
Journal:  Nature       Date:  2010-05-19       Impact factor: 49.962

6.  A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus.

Authors:  Damien Chaussabel; Charles Quinn; Jing Shen; Pinakeen Patel; Casey Glaser; Nicole Baldwin; Dorothee Stichweh; Derek Blankenship; Lei Li; Indira Munagala; Lynda Bennett; Florence Allantaz; Asuncion Mejias; Monica Ardura; Ellen Kaizer; Laurence Monnet; Windy Allman; Henry Randall; Diane Johnson; Aimee Lanier; Marilynn Punaro; Knut M Wittkowski; Perrin White; Joseph Fay; Goran Klintmalm; Octavio Ramilo; A Karolina Palucka; Jacques Banchereau; Virginia Pascual
Journal:  Immunity       Date:  2008-07-18       Impact factor: 31.745

7.  A narrow repertoire of transcriptional modules responsive to pyogenic bacteria is impaired in patients carrying loss-of-function mutations in MYD88 or IRAK4.

Authors:  Laia Alsina; Elisabeth Israelsson; Matthew C Altman; Kristen K Dang; Pegah Ghandil; Laura Israel; Horst von Bernuth; Nicole Baldwin; Huanying Qin; Zongbo Jin; Romain Banchereau; Esperanza Anguiano; Alexei Ionan; Laurent Abel; Anne Puel; Capucine Picard; Virginia Pascual; Jean Laurent Casanova; Damien Chaussabel
Journal:  Nat Immunol       Date:  2014-10-26       Impact factor: 25.606

Review 8.  Experimental and natural infections in MyD88- and IRAK-4-deficient mice and humans.

Authors:  Horst von Bernuth; Capucine Picard; Anne Puel; Jean-Laurent Casanova
Journal:  Eur J Immunol       Date:  2012-12       Impact factor: 5.532
  8 in total

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