Literature DB >> 25388579

[Interplay between primary cilia and cell cycle].

Nathalie Delgehyr1, Nathalie Spassky1.   

Abstract

The primary cilium is often associated with the phases G0 and G1 of the cellular cycle in most of the cells. So, recent studies show that its formation and its resorption are closely linked to molecular actors of the cellular cycle, as for example Aurora A or PLK1 (polo-like kinase 1). Furthermore, its resorption seems to be critical for the progress of the phase S and the cellular determination, in particular in the case of neural stem cells. Finally, the primary cilium acts as a cellular antenna allowing to transmit numerous signal pathways which, in their turn, contribute to the cellular fate.
© 2014 médecine/sciences – Inserm.

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Year:  2014        PMID: 25388579     DOI: 10.1051/medsci/20143011011

Source DB:  PubMed          Journal:  Med Sci (Paris)        ISSN: 0767-0974            Impact factor:   0.818


  1 in total

Review 1.  The essential role of primary cilia in cerebral cortical development and disorders.

Authors:  Siling Liu; Mia X Trupiano; Jeremy Simon; Jiami Guo; E S Anton
Journal:  Curr Top Dev Biol       Date:  2021-01-25       Impact factor: 4.897

  1 in total

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