Literature DB >> 25378221

The use of an extract of Hypericum perforatum and Azadirachta indica in a neuropathic patient with advanced diabetic foot.

Maria Letizia Iabichella1, Claudio Caruso2, Marzia Lugli1.   

Abstract

The successful use of an extract of Hypericum flowers (Hypericum perforatum) and nimh oil (Azadirachta indica; Hyperoil) in foot wounds with exposed bone in a patient with bilateral advanced diabetic ulcers, has been reported previously. It was hypothesised that this amelioration was linked with the improved glycaemic control and peripheral microvascular circulation. In this case report, the surprisingly successful outcome of another patient using Hyperoil for infection damaged diabetic foot, without prior use of surgical procedure, is described. The patient had no macrovascular pattern impairment. Diabetic foot healing paralleled with controlled local infection and enhanced glycaemic control. The outcome of this patient suggests that the effectiveness of this inexpensive therapy using Hyperoil for diabetic foot is not only linked with the presence of severe microvascular disorder, but also with the appropriate local treatment for ulcer being a must for its recovery. 2014 BMJ Publishing Group Ltd.

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Year:  2014        PMID: 25378221      PMCID: PMC4225316          DOI: 10.1136/bcr-2014-205706

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  6 in total

1.  Complementary approaches to estimation of the global burden of diabetes.

Authors:  Nigel Unwin; Leonor Guariguata; David Whiting; Clara Weil
Journal:  Lancet       Date:  2012-04-21       Impact factor: 79.321

2.  Transcutaneous oxygen and carbon dioxide during treatment of critical limb ischemia with iloprost, a prostacyclin derivative.

Authors:  E Melillo; L Iabichella; R Berchiolli; M Ferrari; G Catapano; G Dell'Omo; R Pedrinelli
Journal:  Int J Microcirc Clin Exp       Date:  1995 Mar-Apr

Review 3.  St. John's wort (Hypericum perforatum): a review of the current pharmacological, toxicological, and clinical literature.

Authors:  J M Greeson; B Sanford; D A Monti
Journal:  Psychopharmacology (Berl)       Date:  2001-02       Impact factor: 4.530

4.  The use of an extract of Hypericum perforatum and Azadirachta indica in advanced diabetic foot: an unexpected outcome.

Authors:  Maria Letizia Iabichella
Journal:  BMJ Case Rep       Date:  2013-02-13

5.  Calcium channel blockers blunt postural cutaneous vasoconstriction in hypertensive patients.

Authors:  M L Iabichella; G Dell'Omo; E Melillo; R Pedrinelli
Journal:  Hypertension       Date:  1997-03       Impact factor: 10.190

6.  Clinical outcomes of isolated lower extremity or foot burns in diabetic versus non-diabetic patients: a 10-year retrospective analysis.

Authors:  Zachary Kimball; Sachin Patil; Hani Mansour; Michael A Marano; Sylvia J Petrone; Ronald S Chamberlain
Journal:  Burns       Date:  2012-07-11       Impact factor: 2.744

  6 in total

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