Literature DB >> 23413284

The use of an extract of Hypericum perforatum and Azadirachta indica in advanced diabetic foot: an unexpected outcome.

Maria Letizia Iabichella1.   

Abstract

This is the first case reporting the results of using an extract of Hypericum flowers (Hypericum perforatum) and neem oil (Azadirachta indica) in foot wounds with exposed bone in a patient with bilateral advanced diabetic ulcers. The effective use of this cheap treatment in patients with diabetic lesions on the feet, if confirmed in a wide controlled study, might allow the caregivers to take care of patients at home.

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Year:  2013        PMID： 23413284      PMCID： PMC3604463          DOI： 10.1136/bcr-2012-007299

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  13 in total

1.  Transcutaneous oxygen and carbon dioxide during treatment of critical limb ischemia with iloprost, a prostacyclin derivative.

Authors:  E Melillo; L Iabichella; R Berchiolli; M Ferrari; G Catapano; G Dell'Omo; R Pedrinelli
Journal:  Int J Microcirc Clin Exp       Date:  1995 Mar-Apr

2.  Antibacterial activity of selected medicinal plants against multiple antibiotic resistant uropathogens: a study from Kolli Hills, Tamil Nadu, India.

Authors:  A S Narayanan; S S S Raja; K Ponmurugan; S C Kandekar; K Natarajaseenivasan; A Maripandi; Q A Mandeel
Journal:  Benef Microbes       Date:  2011-09       Impact factor: 4.205

Review 3.  St. John's wort (Hypericum perforatum): a review of the current pharmacological, toxicological, and clinical literature.

Authors:  J M Greeson; B Sanford; D A Monti
Journal:  Psychopharmacology (Berl)       Date:  2001-02       Impact factor: 4.530

4.  Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis.

Authors:  Christoph M Schempp; Vladimir Kirkin; Birgit Simon-Haarhaus; Astrid Kersten; Judit Kiss; Christian C Termeer; Bernhard Gilb; Thomas Kaufmann; Christoph Borner; Jonathan P Sleeman; Jan C Simon
Journal:  Oncogene       Date:  2002-02-14       Impact factor: 9.867

5.  Hyperforin, a bio-active compound of St. John's Wort, is a new inhibitor of angiogenesis targeting several key steps of the process.

Authors:  Beatriz Martínez-Poveda; Ana R Quesada; Miguel Angel Medina
Journal:  Int J Cancer       Date:  2005-12-10       Impact factor: 7.396

6.  Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines.

Authors:  Katarina Hostanska; Juergen Reichling; Silvia Bommer; Michel Weber; Reinhard Saller
Journal:  Eur J Pharm Biopharm       Date:  2003-07       Impact factor: 5.571

7.  Hyperforin inhibits cancer invasion and metastasis.

Authors:  Massimo Donà; Isabella Dell'Aica; Elga Pezzato; Luigi Sartor; Fiorella Calabrese; Mila Della Barbera; Arianna Donella-Deana; Giovanni Appendino; Anna Borsarini; Rosy Caniato; Spiridione Garbisa
Journal:  Cancer Res       Date:  2004-09-01       Impact factor: 12.701

8.  Post-surgical scalp wounds with exposed bone treated with a plant-derived wound therapeutic.

Authors:  S Läuchli; J Hafner; C Wehrmann; L E French; T Hunziker
Journal:  J Wound Care       Date:  2012-05       Impact factor: 2.072

9.  [Use of neem extract in the control of acariasis by Myobia musculi Schranck (Acari: Miobidae) and Myocoptes musculinus Koch (Acari: Listrophoridae) in mice (Mus musculus var. albina L.)].

Authors:  Ana C G dos Santos; Onaldo G Rodrigues; Lúcio V C de Araojo; Sandra B dos Santos; Rita M S N de C Guerra; Matheus L T Feitosa; C Teixeira Whaubtyfran; Arina Santos-Ribeiro
Journal:  Neotrop Entomol       Date:  2006 Mar-Apr       Impact factor: 1.434

10.  Hyperforin, an Anti-Inflammatory Constituent from St. John's Wort, Inhibits Microsomal Prostaglandin E(2) Synthase-1 and Suppresses Prostaglandin E(2) Formation in vivo.

Authors:  Andreas Koeberle; Antonietta Rossi; Julia Bauer; Friederike Dehm; Luisella Verotta; Hinnak Northoff; Lidia Sautebin; Oliver Werz
Journal:  Front Pharmacol       Date:  2011-02-18       Impact factor: 5.810
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  7 in total

1.  Management of acute skin toxicity with Hypericum perforatum and neem oil during platinum-based concurrent chemo-radiation in head and neck cancer patients.

Authors:  Pierfrancesco Franco; Monica Rampino; Oliviero Ostellino; Marina Schena; Giancarlo Pecorari; Paolo Garzino Demo; Massimo Fasolis; Francesca Arcadipane; Stefania Martini; Chiara Cavallin; Mario Airoldi; Umberto Ricardi
Journal:  Med Oncol       Date:  2017-01-18       Impact factor: 3.064

2.  The use of an extract of Hypericum perforatum and Azadirachta indica in a neuropathic patient with advanced diabetic foot.

Authors:  Maria Letizia Iabichella; Claudio Caruso; Marzia Lugli
Journal:  BMJ Case Rep       Date:  2014-11-06

Review 3.  A multidisciplinary approach to scars: a narrative review.

Authors:  Emiliano Zanier; Bruno Bordoni
Journal:  J Multidiscip Healthc       Date:  2015-08-12

4.  Hypericum perforatum and neem oil for the management of acute skin toxicity in head and neck cancer patients undergoing radiation or chemo-radiation: a single-arm prospective observational study.

Authors:  Pierfrancesco Franco; Ilenia Potenza; Francesco Moretto; Mattia Segantin; Mario Grosso; Antonello Lombardo; Daniela Taricco; Patrizia Vallario; Andrea Riccardo Filippi; Monica Rampino; Umberto Ricardi
Journal:  Radiat Oncol       Date:  2014-12-29       Impact factor: 3.481

5.  Use of Neem oil and Hypericum perforatum for treatment of calcinosis-related skin ulcers in systemic sclerosis.

Authors:  Dilia Giuggioli; Federica Lumetti; Amelia Spinella; Emanuele Cocchiara; Gianluca Sighinolfi; Giorgia Citriniti; Michele Colaci; Carlo Salvarani; Clodoveo Ferri
Journal:  J Int Med Res       Date:  2019-12-25       Impact factor: 1.671

Review 6.  Protective Role of St. John's Wort and Its Components Hyperforin and Hypericin against Diabetes through Inhibition of Inflammatory Signaling: Evidence from In Vitro and In Vivo Studies.

Authors:  Michela Novelli; Pellegrino Masiello; Pascale Beffy; Marta Menegazzi
Journal:  Int J Mol Sci       Date:  2020-10-30       Impact factor: 5.923

7.  Plant Leaves Extract Irrigation on Wound Healing in Diabetic Foot Ulcers.

Authors:  Muthu Srinivasan Jayalakshmi; P Thenmozhi; R Vijayaraghavan
Journal:  Evid Based Complement Alternat Med       Date:  2021-05-11       Impact factor: 2.629
  7 in total

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