Literature DB >> 25370663

A hardware investigation of robotic SPECT for functional and molecular imaging onboard radiation therapy systems.

Susu Yan1, James Bowsher2, MengHeng Tough1, Lin Cheng3, Fang-Fang Yin2.   

Abstract

PURPOSE: To construct a robotic SPECT system and to demonstrate its capability to image a thorax phantom on a radiation therapy flat-top couch, as a step toward onboard functional and molecular imaging in radiation therapy.
METHODS: A robotic SPECT imaging system was constructed utilizing a gamma camera detector (Digirad 2020tc) and a robot (KUKA KR150 L110 robot). An imaging study was performed with a phantom (PET CT Phantom(TM)), which includes five spheres of 10, 13, 17, 22, and 28 mm diameters. The phantom was placed on a flat-top couch. SPECT projections were acquired either with a parallel-hole collimator or a single-pinhole collimator, both without background in the phantom and with background at 1/10th the sphere activity concentration. The imaging trajectories of parallel-hole and pinhole collimated detectors spanned 180° and 228°, respectively. The pinhole detector viewed an off-centered spherical common volume which encompassed the 28 and 22 mm spheres. The common volume for parallel-hole system was centered at the phantom which encompassed all five spheres in the phantom. The maneuverability of the robotic system was tested by navigating the detector to trace the phantom and flat-top table while avoiding collision and maintaining the closest possible proximity to the common volume. The robot base and tool coordinates were used for image reconstruction.
RESULTS: The robotic SPECT system was able to maneuver parallel-hole and pinhole collimated SPECT detectors in close proximity to the phantom, minimizing impact of the flat-top couch on detector radius of rotation. Without background, all five spheres were visible in the reconstructed parallel-hole image, while four spheres, all except the smallest one, were visible in the reconstructed pinhole image. With background, three spheres of 17, 22, and 28 mm diameters were readily observed with the parallel-hole imaging, and the targeted spheres (22 and 28 mm diameters) were readily observed in the pinhole region-of-interest imaging.
CONCLUSIONS: Onboard SPECT could be achieved by a robot maneuvering a SPECT detector about patients in position for radiation therapy on a flat-top couch. The robot inherent coordinate frames could be an effective means to estimate detector pose for use in SPECT image reconstruction.

Entities:  

Mesh:

Year:  2014        PMID: 25370663      PMCID: PMC4209015          DOI: 10.1118/1.4898121

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  22 in total

1.  Multimodality nuclear medicine imaging in three-dimensional radiation treatment planning for lung cancer: challenges and prospects.

Authors:  M T Munley; L B Marks; C Scarfone; G S Sibley; E F Patz; T G Turkington; R J Jaszczak; D R Gilland; M S Anscher; R E Coleman
Journal:  Lung Cancer       Date:  1999-02       Impact factor: 5.705

Review 2.  Robotic surgery: a current perspective.

Authors:  Anthony R Lanfranco; Andres E Castellanos; Jaydev P Desai; William C Meyers
Journal:  Ann Surg       Date:  2004-01       Impact factor: 12.969

3.  From anatomical to biological target volumes: the role of PET in radiation treatment planning.

Authors:  D A X Schinagl; J H A M Kaanders; W J G Oyen
Journal:  Cancer Imaging       Date:  2006-10-31       Impact factor: 3.909

Review 4.  Image-guided radiotherapy: from current concept to future perspectives.

Authors:  David A Jaffray
Journal:  Nat Rev Clin Oncol       Date:  2012-11-20       Impact factor: 66.675

Review 5.  Nuclear imaging of the breast: translating achievements in instrumentation into clinical use.

Authors:  Carrie B Hruska; Michael K O'Connor
Journal:  Med Phys       Date:  2013-05       Impact factor: 4.071

Review 6.  [99mTc]sestamibi and [99mTc]tetrofosmin in oncology: SPET and fusion imaging in lung cancer, malignant lymphomas and brain tumors.

Authors:  O Schillaci; A Spanu; G Madeddu
Journal:  Q J Nucl Med Mol Imaging       Date:  2005-06       Impact factor: 2.346

Review 7.  Cardiac dedicated ultrafast SPECT cameras: new designs and clinical implications.

Authors:  Ernest V Garcia; Tracy L Faber; Fabio P Esteves
Journal:  J Nucl Med       Date:  2011-01-13       Impact factor: 10.057

Review 8.  Particle therapy at the Heidelberg Ion Therapy Center (HIT) - Integrated research-driven university-hospital-based radiation oncology service in Heidelberg, Germany.

Authors:  Stephanie E Combs; Oliver Jäkel; Thomas Haberer; Jürgen Debus
Journal:  Radiother Oncol       Date:  2010-03-11       Impact factor: 6.280

9.  Incorporation of SPECT bone marrow imaging into intensity modulated whole-pelvic radiation therapy treatment planning for gynecologic malignancies.

Authors:  John C Roeske; Anthony Lujan; Richard C Reba; Bill C Penney; S Diane Yamada; Arno J Mundt
Journal:  Radiother Oncol       Date:  2005-07-18       Impact factor: 6.280

Review 10.  Experiences with an application of industrial robotics for accurate patient positioning in proton radiotherapy.

Authors:  C E Allgower; A N Schreuder; J B Farr; A E Mascia
Journal:  Int J Med Robot       Date:  2007-03       Impact factor: 2.547

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.