Literature DB >> 25370633

Dynamic tumor tracking using the Elekta Agility MLC.

Martin F Fast1, Simeon Nill1, James L Bedford1, Uwe Oelfke1.   

Abstract

PURPOSE: To evaluate the performance of the Elekta Agility multileaf collimator (MLC) for dynamic real-time tumor tracking.
METHODS: The authors have developed a new control software which interfaces to the Agility MLC to dynamically program the movement of individual leaves, the dynamic leaf guides (DLGs), and the Y collimators ("jaws") based on the actual target trajectory. A motion platform was used to perform dynamic tracking experiments with sinusoidal trajectories. The actual target positions reported by the motion platform at 20, 30, or 40 Hz were used as shift vectors for the MLC in beams-eye-view. The system latency of the MLC (i.e., the average latency comprising target device reporting latencies and MLC adjustment latency) and the geometric tracking accuracy were extracted from a sequence of MV portal images acquired during irradiation for the following treatment scenarios: leaf-only motion, jaw + leaf motion, and DLG + leaf motion.
RESULTS: The portal imager measurements indicated a clear dependence of the system latency on the target position reporting frequency. Deducting the effect of the target frequency, the leaf adjustment latency was measured to be 38 ± 3 ms for a maximum target speed v of 13 mm/s. The jaw + leaf adjustment latency was 53 ± 3 at a similar speed. The system latency at a target position frequency of 30 Hz was in the range of 56-61 ms for the leaves (v ≤ 31 mm/s), 71-78 ms for the jaw + leaf motion (v ≤ 25 mm/s), and 58-72 ms for the DLG + leaf motion (v ≤ 59 mm/s). The tracking accuracy showed a similar dependency on the target position frequency and the maximum target speed. For the leaves, the root-mean-squared error (RMSE) was between 0.6-1.5 mm depending on the maximum target speed. For the jaw + leaf (DLG + leaf) motion, the RMSE was between 0.7-1.5 mm (1.9-3.4 mm).
CONCLUSIONS: The authors have measured the latency and geometric accuracy of the Agility MLC, facilitating its future use for clinical tracking applications.

Entities:  

Mesh:

Year:  2014        PMID: 25370633     DOI: 10.1118/1.4899175

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  21 in total

1.  Technical Note: In silico and experimental evaluation of two leaf-fitting algorithms for MLC tracking based on exposure error and plan complexity.

Authors:  Vincent Caillet; Ricky O'Brien; Douglas Moore; Per Poulsen; Tobias Pommer; Emma Colvill; Amit Sawant; Jeremy Booth; Paul Keall
Journal:  Med Phys       Date:  2019-03-04       Impact factor: 4.071

2.  Couch and multileaf collimator tracking: A clinical feasibility study for pancreas and liver treatment.

Authors:  Lei Zhang; Thomas LoSasso; Pengpeng Zhang; Margie Hunt; Gig Mageras; Grace Tang
Journal:  Med Phys       Date:  2020-09-11       Impact factor: 4.071

3.  Fast leaf-fitting with generalized underdose/overdose constraints for real-time MLC tracking.

Authors:  Douglas Moore; Dan Ruan; Amit Sawant
Journal:  Med Phys       Date:  2016-01       Impact factor: 4.071

Review 4.  Image-guided radiotherapy and motion management in lung cancer.

Authors:  S S Korreman
Journal:  Br J Radiol       Date:  2015-05-08       Impact factor: 3.039

Review 5.  Stereotactic radiotherapy for early stage non-small cell lung cancer: current standards and ongoing research.

Authors:  Eugenia Vlaskou Badra; Michael Baumgartl; Silvia Fabiano; Aurélien Jongen; Matthias Guckenberger
Journal:  Transl Lung Cancer Res       Date:  2021-04

6.  A dosimetric comparison of real-time adaptive and non-adaptive radiotherapy: A multi-institutional study encompassing robotic, gimbaled, multileaf collimator and couch tracking.

Authors:  Emma Colvill; Jeremy Booth; Simeon Nill; Martin Fast; James Bedford; Uwe Oelfke; Mitsuhiro Nakamura; Per Poulsen; Esben Worm; Rune Hansen; Thomas Ravkilde; Jonas Scherman Rydhög; Tobias Pommer; Per Munck Af Rosenschold; Stephanie Lang; Matthias Guckenberger; Christian Groh; Christian Herrmann; Dirk Verellen; Kenneth Poels; Lei Wang; Michael Hadsell; Thilo Sothmann; Oliver Blanck; Paul Keall
Journal:  Radiother Oncol       Date:  2016-03-22       Impact factor: 6.280

7.  Lung stereotactic body radiotherapy with an MR-linac - Quantifying the impact of the magnetic field and real-time tumor tracking.

Authors:  Martin J Menten; Martin F Fast; Simeon Nill; Cornelis P Kamerling; Fiona McDonald; Uwe Oelfke
Journal:  Radiother Oncol       Date:  2016-05-08       Impact factor: 6.280

8.  Effect of MLC tracking latency on conformal volumetric modulated arc therapy (VMAT) plans in 4D stereotactic lung treatment.

Authors:  James L Bedford; Martin F Fast; Simeon Nill; Fiona M A McDonald; Merina Ahmed; Vibeke N Hansen; Uwe Oelfke
Journal:  Radiother Oncol       Date:  2015-08-13       Impact factor: 6.280

9.  Motion monitoring during a course of lung radiotherapy with anchored electromagnetic transponders : Quantification of inter- and intrafraction motion and variability of relative transponder positions.

Authors:  Daniela Schmitt; Simeon Nill; Falk Roeder; Daniela Gompelmann; Felix Herth; Uwe Oelfke
Journal:  Strahlenther Onkol       Date:  2017-07-21       Impact factor: 3.621

10.  Real-time energy/mass transfer mapping for online 4D dose reconstruction.

Authors:  Peter Ziegenhein; Cornelis Ph Kamerling; Martin F Fast; Uwe Oelfke
Journal:  Sci Rep       Date:  2018-02-26       Impact factor: 4.379

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