Literature DB >> 25370105

The antioxidant methyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate.

Xiang Li1, Zhi-Gang Wang1, Hou-He Chen2, Sheng-Gao Liu1.   

Abstract

The title compound, C18H28O3, was prepared by the reaction of 2,6-di-tert-butylphenol with methyl acrylate under basic conditions using dimethyl sulfoxide as the promoter. The structure of this antioxidant indicates significant strain between the ortho tert-butyl substituents and the phenolic OH group. In spite of the steric crowding of the OH group, it participates in intermolecular hydrogen bonding with the ester carbonyl O atom.

Entities:  

Keywords:  antioxidant; crystal structure; hindered phenol; hydrogen bonding

Year:  2014        PMID: 25370105     DOI: 10.1107/S2053229614021445

Source DB:  PubMed          Journal:  Acta Crystallogr C Struct Chem        ISSN: 2053-2296            Impact factor:   1.172


  2 in total

1.  Methanol extract of Dicranopteris linearis L. leaves impedes acetaminophen-induced liver intoxication partly by enhancing the endogenous antioxidant system.

Authors:  Zainul Amiruddin Zakaria; Farah Hidayah Kamisan; Maizatul Hasyima Omar; Nur Diyana Mahmood; Fezah Othman; Siti Selina Abdul Hamid; Muhammad Nazrul Hakim Abdullah
Journal:  BMC Complement Altern Med       Date:  2017-05-18       Impact factor: 3.659

2.  Crystal structure and Hirshfeld surface analysis of 5-(3,5-di-tert-butyl-4-hy-droxy-phen-yl)-3-phenyl-4,5-di-hydro-1H-pyrazole-1-carboxamide.

Authors:  Ayten R Asgarova
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2019-09-12
  2 in total

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