Literature DB >> 2536635

Human SSAV-related endogenous retroviral element: LTR-like sequence and chromosomal localization to 18q21.

R Brack-Werner1, D E Barton, T Werner, B E Foellmer, C Leib-Mösch, U Francke, V Erfle, R Hehlmann.   

Abstract

A new family of human endogenous retroviral sequences was recently discovered by way of its relationship to the simian sarcoma-associated virus (SSAV). One molecular clone, termed S71, contains sequences related to the genes coding for the group-specific antigens (gag) and polymerase (pol) proteins of SSAV. At the 3' end of this human retroviral element we have now found a 535-bp region which shows features characteristics of a retroviral long terminal repeat, including potential signal sequences essential for transcriptional control. By means of Southern blotting and in situ hybridization, the sequence was mapped to chromosome 18 band q21.

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Year:  1989        PMID： 2536635     DOI： 10.1016/0888-7543(89)90316-9

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  7 in total

1.  Prototypic sequences for human repetitive DNA.

Authors:  J Jurka; J Walichiewicz; A Milosavljevic
Journal:  J Mol Evol       Date:  1992-10       Impact factor: 2.395

2.  Expression and phylogenetic analyses of human endogenous retrovirus HC2 belonging to the HERV-T family in human tissues and cancer cells.

Authors:  Joo-Mi Yi; Heui-Soo Kim
Journal:  J Hum Genet       Date:  2007-02-03       Impact factor: 3.172

3.  Two RFLPs associated with the human endogenous retroviral element S71 on chromosome 18q21.

Authors:  C Leib-Mösch; D Barton; E M Geigl; R Brack-Werner; V Erfle; R Hehlmann; U Francke
Journal:  Nucleic Acids Res       Date:  1989-03-25       Impact factor: 16.971

4.  Computer-assisted prediction, classification, and delimitation of protein binding sites in nucleic acids.

Authors:  K Frech; G Herrmann; T Werner
Journal:  Nucleic Acids Res       Date:  1993-04-11       Impact factor: 16.971

5.  A gene for familial juvenile polyposis maps to chromosome 18q21.1.

Authors:  J R Howe; J C Ringold; R W Summers; F A Mitros; D Y Nishimura; E M Stone
Journal:  Am J Hum Genet       Date:  1998-05       Impact factor: 11.025

Review 6.  Evolution and biological significance of human retroelements.

Authors:  C Leib-Mösch; W Seifarth
Journal:  Virus Genes       Date:  1995       Impact factor: 2.332

7.  The 18q- syndrome: analysis of chromosomes by bivariate flow karyotyping and the PCR reveals a successive set of deletion breakpoints within 18q21.2-q22.2.

Authors:  G A Silverman; S S Schneider; H F Massa; A Flint; M Lalande; J C Leonard; J Overhauser; G van den Engh; B J Trask
Journal:  Am J Hum Genet       Date:  1995-04       Impact factor: 11.025
  7 in total

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