Literature DB >> 2536218

On the possibility of pleiotropic monogenic control of hereditary polyposis and primary cancer of the colon.

E K Ginsburg1, T I Axenovich, B A Altshouler, M D Bazhenova.   

Abstract

The results of the segregation analysis of hereditary adenomatous polyposis and primary cancer of the colon are given, taking into account the age-dependent manifestation of genotypes and the specificity of pedigree sampling. The results are used for testing the hypothesis of pleiotropic monogenic control of these two colon pathologies.

Entities:  

Mesh：

Year:  1989        PMID： 2536218      PMCID： PMC1715412     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  9 in total

1.  Sampling considerations in the gathering and analysis of pedigree data.

Authors:  R C Elston; E Sobel
Journal:  Am J Hum Genet       Date:  1979-01       Impact factor: 11.025

2.  Genetics and colon cancer.

Authors:  H T Lynch; H Guirgis; M Swartz; J Lynch; A J Krush; A R Kaplan
Journal:  Arch Surg       Date:  1973-05

3.  [Familial incidence of intestinal carcinoma].

Authors:  R Feinstein; H Fahrländer
Journal:  Schweiz Med Wochenschr       Date:  1972-11-18

4.  A general model for the genetic analysis of pedigree data.

Authors:  R C Elston; J Stewart
Journal:  Hum Hered       Date:  1971       Impact factor: 0.444

5.  Inherited colon cancer: clinical implications.

Authors:  S Z Kussin; M Lipkin; S J Winawer
Journal:  Am J Gastroenterol       Date:  1979-10       Impact factor: 10.864

6.  [Genetic problems of hereditary polyposis of the large intestine. II. Characteristics of the population genetics].

Authors:  M D Bazhenova; S I Kozlova; B A Al'tshuler; A M Nikitin; G G Tatishvili
Journal:  Genetika       Date:  1985-09

7.  Segregation analysis of congenital glaucoma: approach by two differential models.

Authors:  F Demenais; R C Elston; C Bonaiti; M L Briard; E B Kaplan; K K Namboodiri
Journal:  Am J Hum Genet       Date:  1981-03       Impact factor: 11.025

8.  Neural tube defects in France: segregation analysis.

Authors:  F Demenais; M Le Merrer; M L Briard; R C Elston
Journal:  Am J Med Genet       Date:  1982-03

9.  [Genetic problems of hereditary polyposis of the large intestine. I. An analysis of the interrelation with intestinal cancer].

Authors:  B A Al'tshuler; A M Nikitin; M D Bazhenova; G G Tatishvili
Journal:  Genetika       Date:  1985-08
  9 in total
  1 in total

1.  Simulation of recessive transmission in the combined data of polyposis coli and cancer of the colon.

Authors:  K H Sit
Journal:  Am J Hum Genet       Date:  1990-01       Impact factor: 11.025
  1 in total

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