Literature DB >> 2535473

The linear tetrasaccharide, Gal beta 1-4GlcNAc beta 1-6Gal beta 1-4GlcNAc, isolated from radiolabeled teratocarcinoma poly-N-acetyllactosaminoglycan resists the action of E. freundii endo-beta-galactosidase.

O Renkonen1, L Penttilä, A Makkonen, R Niemelä, A Leppänen, J Helin, A Vainio.   

Abstract

A novel linear tetrasaccharide, Gal beta 1-4GlcNAc beta 1-6Gal beta 1-4GlcNAc, was isolated from partial acid hydrolysates of metabolically labeled poly-N-acetyllactosaminoglycans of murine teratocarcinoma cells. It was characterized by exo-glycosidase sequencing and by mild acid hydrolysis followed by identification of all partial cleavage products. The tetrasaccharide, and likewise labelled GlcNAc beta 1-6Gal beta 1-4GlcNAc, resisted the action of endo-beta-galactosidase (EC 3.2.1.103) from E. freundii at a concentration of 125 mU/ml, while the isomeric, radioactive teratocarcinoma saccharides Gal beta 1-4GlcNAc beta 1-3Gal beta 1-4GlcNAc and GlcNAc beta 1-3Gal beta 1-4GlcNAc were cleaved in the expected manner.

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Year:  1989        PMID： 2535473     DOI： 10.1007/bf01047895

Source DB:  PubMed          Journal:  Glycoconj J        ISSN： 0282-0080            Impact factor:   2.916


  19 in total

1.  THE EXTRACELLULAR GLYCOSIDASES OF DIPLOCOCCUS PNEUMONIAE. I. PURIFICATION AND PROPERTIES OF A NEURAMINIDASE AND A BETA-GALACTOSIDASE. ACTION ON THE ALPHA-1-ACID GLYCOPROTEIN OF HUMAN PLASMA.

Authors:  R C HUGHES; R W JEANLOZ
Journal:  Biochemistry       Date:  1964-10       Impact factor: 3.162

2.  Studies on the monosaccharide sequence of the serum glycoprotein fetuin.

Authors:  R G SPIRO
Journal:  J Biol Chem       Date:  1962-03       Impact factor: 5.157

3.  Polysaccharides of embryonal carcinoma cells of line PC 13.

Authors:  O Renkonen
Journal:  Biochem Soc Trans       Date:  1983-06       Impact factor: 5.407

4.  Endo-beta-galactosidase from Escherichia freundii.

Authors:  Y T Li; H Nakagawa; M Kitamikado; S C Li
Journal:  Methods Enzymol       Date:  1982       Impact factor: 1.600

5.  Resolution of nucleotide sugars and oligosaccharides by lectin affinity chromatography.

Authors:  D A Blake; I J Goldstein
Journal:  Anal Biochem       Date:  1980-02       Impact factor: 3.365

6.  Specific cell-surface labeling of polyglycosyl chains in human erythrocytes and HL-60 cells using endo-beta-galactosidase and galactosyltransferase.

Authors:  J Viitala; J Finne
Journal:  Eur J Biochem       Date:  1984-01-16

7.  A series of human erythrocyte glycosphingolipids reacting to the monoclonal antibody directed to a developmentally regulated antigen SSEA-1.

Authors:  R Kannagi; E Nudelman; S B Levery; S Hakomori
Journal:  J Biol Chem       Date:  1982-12-25       Impact factor: 5.157

8.  Alkaline phosphatase activity in mouse teratoma.

Authors:  E G Berstine; M L Hooper; S Grandchamp; B Ephrussi
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205

9.  Structure of branched lactosaminoglycan, the carbohydrate moiety of band 3 isolated from adult human erythrocytes.

Authors:  M Fukuda; A Dell; J E Oates; M N Fukuda
Journal:  J Biol Chem       Date:  1984-07-10       Impact factor: 5.157

10.  Cell-associated glycosaminoglycans of human teratocarcinoma-derived cells of line PA 1.

Authors:  M L Rasilo; O Renkonen
Journal:  Eur J Biochem       Date:  1982-04-01
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  5 in total

1.  Construction of linear GlcNAc beta 1-6Gal beta 1-OR type oligosaccharides by partial cleavage of GlcNAc beta 1-3(GlcNAc beta 1-6)Gal beta 1-OR sequences with jack bean beta-N-acetylhexosaminidase.

Authors:  O Renkonen; R Niemelä; A Leppänen; H Maaheimo; A Seppo; L Penttilä; A Vilkman
Journal:  Glycoconj J       Date:  1991-08       Impact factor: 2.916

2.  Oligo-N-acetyllactosaminoglycans bearing Gal beta 1-4(Fuc alpha 1-3)GlcNAc sequences reveal lower affinities than their nonfucosylated, or alpha(1-2) fucosylated counterparts for immobilized wheat germ agglutinin.

Authors:  O Renkonen; J Helin; L Penttilä; H Maaheimo; R Niemelä; A Leppänen; A Seppo; K Hård
Journal:  Glycoconj J       Date:  1991-08       Impact factor: 2.916

3.  Single mid-chain GlcNAc beta 1-6Gal beta 1-4R sequences of linear oligosaccharides are resistant to endo-beta-galactosidase of Bacteroides fragilis.

Authors:  O Renkonen; L Penttilä; R Niemelä; A Leppänen
Journal:  Glycoconj J       Date:  1991-08       Impact factor: 2.916

4.  Glycosylation of the envelope glycoprotein gp130 of simian immunodeficiency virus from sooty mangabey (Cercocebus atys).

Authors:  C Holschbach; J Schneider; H Geyer
Journal:  Biochem J       Date:  1990-05-01       Impact factor: 3.857

5.  alpha 1,3-Fucosylation of branched blood group I-type oligo-(N-acetyllactosamino)glycans by human milk transferases is restricted to distal N-acetyllactosamine units: the resulting isomers are separated by WGA-agarose chromatography.

Authors:  R Niemelä; J Natunen; E Brotherus; A Saarikangas; O Renkonen
Journal:  Glycoconj J       Date:  1995-02       Impact factor: 2.916
  5 in total

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