Nader Shaikh1, Ellen R Wald. 1. General Academic Pediatrics, Children's Hospital of Pittsburgh, 3414 Fifth Ave, Suite 301, Pittsburgh, PA, USA, 15213.
Abstract
BACKGROUND: The efficacy of decongestants, antihistamines and nasal irrigation in children with clinically diagnosed acute sinusitis has not been systematically evaluated. OBJECTIVES: To determine the efficacy of decongestants, antihistamines or nasal irrigation in improving symptoms of acute sinusitis in children. SEARCH METHODS: We searched CENTRAL (2014, Issue 5), MEDLINE (1950 to June week 1, 2014) and EMBASE (1950 to June 2014). SELECTION CRITERIA: We included randomized controlled trials (RCTs) and quasi-RCTs, which evaluated children younger than 18 years of age with acute sinusitis, defined as 10 to 30 days of rhinorrhea, congestion or daytime cough. We excluded trials of children with chronic sinusitis and allergic rhinitis. DATA COLLECTION AND ANALYSIS: Two review authors independently assessed each study for inclusion. MAIN RESULTS: Of the 662 studies identified through the electronic searches and handsearching, none met all the inclusion criteria. AUTHORS' CONCLUSIONS: There is no evidence to determine whether the use of antihistamines, decongestants or nasal irrigation is efficacious in children with acute sinusitis. Further research is needed to determine whether these interventions are beneficial in the treatment of children with acute sinusitis.
BACKGROUND: The efficacy of decongestants, antihistamines and nasal irrigation in children with clinically diagnosed acute sinusitis has not been systematically evaluated. OBJECTIVES: To determine the efficacy of decongestants, antihistamines or nasal irrigation in improving symptoms of acute sinusitis in children. SEARCH METHODS: We searched CENTRAL (2014, Issue 5), MEDLINE (1950 to June week 1, 2014) and EMBASE (1950 to June 2014). SELECTION CRITERIA: We included randomized controlled trials (RCTs) and quasi-RCTs, which evaluated children younger than 18 years of age with acute sinusitis, defined as 10 to 30 days of rhinorrhea, congestion or daytime cough. We excluded trials of children with chronic sinusitis and allergic rhinitis. DATA COLLECTION AND ANALYSIS: Two review authors independently assessed each study for inclusion. MAIN RESULTS: Of the 662 studies identified through the electronic searches and handsearching, none met all the inclusion criteria. AUTHORS' CONCLUSIONS: There is no evidence to determine whether the use of antihistamines, decongestants or nasal irrigation is efficacious in children with acute sinusitis. Further research is needed to determine whether these interventions are beneficial in the treatment of children with acute sinusitis.
Authors: David Rabago; Aleksandra Zgierska; Marlon Mundt; Bruce Barrett; James Bobula; Rob Maberry Journal: J Fam Pract Date: 2002-12 Impact factor: 0.493
Authors: Olavo de Godoy Mion; João Ferreira de Mello; Daniel Lorena Dutra; Nilvano Alves de Andrade; Washington Luiz de Cerqueira Almeida; Wilma Teresinha Anselmo-Lima; Leonardo Lopes Balsalobre Filho; Jair de Carvalho E Castro; Roberto Eustáquio Dos Santos Guimarães; Marcus Miranda Lessa; Sérgio Fabrício Maniglia; Roberto Campos Meireles; Márcio Nakanishi; Shirley Shizue Nagata Pignatari; Renato Roithmann; Fabrizio Ricci Romano; Rodrigo de Paula Santos; Marco César Jorge Dos Santos; Edwin Tamashiro Journal: Braz J Otorhinolaryngol Date: 2017-01-21