Literature DB >> 25343826

Rationale of mesenchymal stem cell therapy in kidney injury.

Susanne V Fleig1, Benjamin D Humphreys.   

Abstract

Hundreds of clinical trials are currently investigating the potential for mesenchymal stem cells (MSC) to treat human disease, including kidney disease. There is tremendous excitement over the therapeutic potential of this form of stem cell therapy and an improving understanding of how MSC act. This review will summarize our current knowledge concerning the mechanisms by which MSC accelerate kidney repair after acute injury. It will also survey the current MSC clinical trial landscape in nephrology. Finally, future challenges to a widespread application of MSC therapies for patients with kidney injury will be outlined. 2014 S. Karger AG, Basel.

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Year:  2014        PMID： 25343826     DOI： 10.1159/000363680

Source DB:  PubMed          Journal:  Nephron Clin Pract        ISSN： 1660-2110


  26 in total

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Authors:  William F Loomis
Journal:  Dev Biol       Date:  2015-04-11       Impact factor: 3.582

2.  Mesenchymal Stem Cell-derived Extracellular Vesicles for Renal Repair.

Authors:  Arash Aghajani Nargesi; Lilach O Lerman; Alfonso Eirin
Journal:  Curr Gene Ther       Date:  2017       Impact factor: 4.391

Review 3.  Renoprotective approaches and strategies in acute kidney injury.

Authors:  Yuan Yang; Meifang Song; Yu Liu; Hong Liu; Lin Sun; Youming Peng; Fuyou Liu; Manjeri A Venkatachalam; Zheng Dong
Journal:  Pharmacol Ther       Date:  2016-04-22       Impact factor: 12.310

4.  Exosomes to the Rescue.

Authors:  Jessica Rossol-Allison; Christopher J Ward
Journal:  J Am Soc Nephrol       Date:  2015-04-21       Impact factor: 10.121

Review 5.  Renal extracellular vesicles: from physiology to clinical application.

Authors:  E E Morrison; M A Bailey; J W Dear
Journal:  J Physiol       Date:  2016-05-27       Impact factor: 5.182

6.  Infusion of Valproic Acid Into the Renal Medulla Activates Stem Cell Population and Attenuates Salt-Sensitive Hypertension in Dahl S Rats.

Authors:  Zhengchao Wang; Qing Zhu; Weili Wang; Fan Yi; Pin-Lan Li; Krishna M Boini; Ningjun Li
Journal:  Cell Physiol Biochem       Date:  2017-07-11

Review 7.  Recent Updates on Mesenchymal Stem Cell Based Therapy for Acute Renal Failure.

Authors:  Asmaa Missoum
Journal:  Curr Urol       Date:  2020-01-07

8.  Adipose-derived mesenchymal stem cell-derived exosomes alleviate overwhelming systemic inflammatory reaction and organ damage and improve outcome in rat sepsis syndrome.

Authors:  Chia-Lo Chang; Pei-Hsun Sung; Kuan-Hung Chen; Pei-Lin Shao; Chih-Chao Yang; Ben-Chung Cheng; Kun-Chen Lin; Chih-Hung Chen; Han-Tan Chai; Hsueh-Wen Chang; Hon-Kan Yip; Hong-Hwa Chen
Journal:  Am J Transl Res       Date:  2018-04-15       Impact factor: 4.060

9.  Adipose-derived mesenchymal stem cell-derived exosomes markedly protected the brain against sepsis syndrome induced injury in rat.

Authors:  Chia-Lo Chang; Hong-Hwa Chen; Kuan-Hung Chen; John Y Chiang; Yi-Chen Li; Hung-Sheng Lin; Pei-Hsun Sung; Hon-Kan Yip
Journal:  Am J Transl Res       Date:  2019-07-15       Impact factor: 4.060

Review 10.  Noninvasive assessment of renal fibrosis by magnetic resonance imaging and ultrasound techniques.

Authors:  Kai Jiang; Christopher M Ferguson; Lilach O Lerman
Journal:  Transl Res       Date:  2019-04-22       Impact factor: 7.012
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