Literature DB >> 25340310

Diastereoselective synthesis of α-(aminomethyl)-γ-butyrolactones via a catalyst-free aminolactonization.

P Veeraraghavan Ramachandran1, Daniel R Nicponski.   

Abstract

An auto-catalytic domino reaction, presumably involving an aza-Michael reaction, proton transfer, and lactonization, furnishing α-(aminomethyl)-γ-butyrolactones in near quantitative yields and excellent diastereoselectivity is described.

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Year:  2014        PMID: 25340310     DOI: 10.1039/c4cc05765a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Rhodium-catalyzed regioselective addition of the ortho C-H bond in aromatic amides to the C-C double bond in α,β-unsaturated γ-lactones and dihydrofurans.

Authors:  Kaname Shibata; Naoto Chatani
Journal:  Chem Sci       Date:  2015-09-25       Impact factor: 9.825

  1 in total

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