| Literature DB >> 25337628 |
Jittra Suthiwong1, Siripit Pitchuanchom, Wareeporn Wattanawongdon, Chariya Hahnvajanawong, Chavi Yenjai.
Abstract
Five new compounds, including pteroloterins A-C (1, 3, and 4), 1β-acetoxytaepeenin C (2), and 8aα-hydroxycadinenal (5), and 11 known compounds were isolated from the root bark of Pterolobium macropterum. All compounds were evaluated for cytotoxicity against the cholangiocarcinoma cell lines. Compound 9 showed weak cytotoxicity against the KKU-M139 cell line with an IC50 value of 23.24 ± 0.18 μM and showed no activity against normal cells.Entities:
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Year: 2014 PMID： 25337628 DOI： 10.1021/np500476h
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050