| Literature DB >> 25333008 |
Jeong Seon Ryu1, Azra Memon1, Seul-Ki Lee1.
Abstract
Excision repair cross-complementing group 1 (ERCC1) is known to be a key player in nucleotide excision repair (NER) pathway. Its prognostic or predictive relevance has been extensively investigated in cancer patients including non-small-cell lung cancer. However, several questions should be addressed before its clinical application as biomarker for patient classification or guiding platinum treatment.Entities:
Keywords: Biomarker; excision repair cross-complementing group 1 (ERCC1); non-small-cell lung cancer; personalized medicine
Year: 2014 PMID: 25333008 PMCID: PMC4200610 DOI: 10.3978/j.issn.2305-5839.2013.12.01
Source DB: PubMed Journal: Ann Transl Med ISSN: 2305-5839