Literature DB >> 25332896

Obesity in kidney disease: A heavyweight opponent.

Raphael Jose Ferreira Felizardo1, Marina Burgos da Silva1, Cristhiane Favero Aguiar1, Niels Olsen Saraiva Câmara1.   

Abstract

Obesity is an important worldwide challenge that must be faced in most developed and developing countries because of unhealthy nutritional habits. The consequences of obesity and being overweight are observed in different organs, but the kidney is one of the most affected. Excess adipose tissue causes hemodynamic alterations in the kidney that can result in renal disease. However, obesity is also commonly associated with other comorbidities such as chronic inflammation, hypertension and diabetes. This association of several aggravating factors is still a matter of concern in clinical and basic research because the pathophysiologic mechanisms surrounding chronic kidney disease development in obese patients remain unclear. This review will discuss the consequences of obesity in the context of renal injury.

Entities:  

Keywords:  Diabetes; Kidney disease; Obesity; Overweight; Renin-angiotensin system

Year:  2014        PMID： 25332896      PMCID： PMC4202492          DOI： 10.5527/wjn.v3.i3.50

Source DB:  PubMed          Journal:  World J Nephrol        ISSN： 2220-6124


  162 in total

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Review 2.  Improving the efficacy of RAAS blockade in patients with chronic kidney disease.

Authors:  Hiddo J Lambers Heerspink; Martin H de Borst; Stephan J L Bakker; Gerjan J Navis
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3.  Plasma aldosterone is independently associated with the metabolic syndrome.

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Journal:  Hypertension       Date:  2006-06-19       Impact factor: 10.190

Review 4.  Advanced glycation end products and diabetic nephropathy.

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Journal:  Am J Ther       Date:  2005 Nov-Dec       Impact factor: 2.688

5.  Inflammasome is a central player in the induction of obesity and insulin resistance.

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Journal:  Kidney Int       Date:  1995-03       Impact factor: 10.612

7.  CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity.

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Journal:  Nat Med       Date:  2009-07-26       Impact factor: 53.440

8.  Exacerbation of albuminuria and renal fibrosis in subtotal renal ablation model of adiponectin-knockout mice.

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9.  Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study.

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10.  Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.

Authors:  James M Luther; Pengcheng Luo; Zuofei Wang; Samuel E Cohen; Hyung-Suk Kim; Agnes B Fogo; Nancy J Brown
Journal:  Kidney Int       Date:  2012-05-23       Impact factor: 10.612
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  12 in total

1.  Urinary fibrogenic cytokines ET-1 and TGF-β1 are associated with urinary angiotensinogen levels in obese children.

Authors:  Liane Correia-Costa; Manuela Morato; Teresa Sousa; Dina Cosme; João Tiago Guimarães; António Guerra; Franz Schaefer; Alberto Caldas Afonso; Ana Azevedo; António Albino-Teixeira
Journal:  Pediatr Nephrol       Date:  2015-10-19       Impact factor: 3.714

Review 2.  The kidney in obesity.

Authors:  Josep Redon; Empar Lurbe
Journal:  Curr Hypertens Rep       Date:  2015-06       Impact factor: 5.369

3.  Matrix Metalloproteinase Neutrophil Gelatinase-Associated Lipocalin Complex Predicts Atrial Fibrillation Recurrence after Electrical Cardioversion in Obese Patients.

Authors:  Elzbieta Mlodawska; Anna Tomaszuk-Kazberuk; Paulina Lopatowska; Ewa Waszkiewicz; Hanna Bachorzewska-Gajewska; Jolanta Malyszko; Ewelina Michniewicz; Slawomir Dobrzycki; Wlodzimierz Jerzy Musial
Journal:  Cardiorenal Med       Date:  2016-08-12       Impact factor: 2.041

Review 4.  Obesity-related glomerulopathy: pathogenesis, pathologic, clinical characteristics and treatment.

Authors:  Tianhua Xu; Zitong Sheng; Li Yao
Journal:  Front Med       Date:  2017-08-08       Impact factor: 4.592

5.  Leptin deficiency down-regulates IL-23 production in glomerular podocytes resulting in an attenuated immune response in nephrotoxic serum nephritis.

Authors:  Kei Goto; Yoshikatsu Kaneko; Yuya Sato; Tadashi Otsuka; Suguru Yamamoto; Shin Goto; Keiko Yamamoto; Tadashi Yamamoto; Hiroshi Kawachi; Michael P Madaio; Ichiei Narita
Journal:  Int Immunol       Date:  2015-11-13       Impact factor: 4.823

6.  Anti-Inflammatory Effects of Ang-(1-7) in Ameliorating HFD-Induced Renal Injury through LDLr-SREBP2-SCAP Pathway.

Authors:  Yaning Zheng; Lin Tang; Wenhan Huang; Ruyu Yan; Feifeng Ren; Lei Luo; Ling Zhang
Journal:  PLoS One       Date:  2015-08-20       Impact factor: 3.240

7.  Precocious obesity predisposes the development of more severe cisplatin-induced acute kidney injury in young adult mice.

Authors:  Rosemara S Ribeiro; Clevia S Passos; Antônio S Novaes; Edgar Maquigussa; Maria A Glória; Iria Visoná; Olinda Ykuta; Lila M Oyama; Mirian A Boim
Journal:  PLoS One       Date:  2017-03-30       Impact factor: 3.240

8.  Resveratrol intake during pregnancy and lactation re-programs adiposity and ameliorates leptin resistance in male progeny induced by maternal high-fat/high sucrose plus postnatal high-fat/high sucrose diets via fat metabolism regulation.

Authors:  Ta-Yu Liu; Hong-Ren Yu; Ching-Chou Tsai; Li-Tung Huang; Chih-Cheng Chen; Jium-Ming Sheen; Mao-Meng Tiao; You-Lin Tain; I-Chun Lin; Yun-Ju Lai; Yu-Ju Lin; Te-Yao Hsu
Journal:  Lipids Health Dis       Date:  2020-07-25       Impact factor: 3.876

9.  Impact of a Community-Based Weight Loss Program on Renal Function.

Authors:  Tiffany E Schwasinger-Schmidt; Georges Elhomsy; Bobbie G Paull-Forney
Journal:  Cureus       Date:  2020-05-13

10.  Reduction in Urinary Chemokine (C-C Motif) Ligand 2 (CCL2) After Surgery-Induced Weight Loss.

Authors:  Surita Binti Said; Guo Hou Loo; Nik Ritza Kosai; Reynu Rajan; Rozita Mohd; Asrul Abdul Wahab; Shamsul Azhar Shah
Journal:  Sci Rep       Date:  2020-01-21       Impact factor: 4.379
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