Marek Rękas1, Kamilla Barchan-Kucia2, Joanna Konopińska3, Zofia Mariak3, Tomasz Żarnowski2. 1. a Department of Ophthalmology , Military Institute of Medicine in Warsaw , Warsaw , Poland . 2. b Department of Glaucoma Diagnostic and Microsurgery , Medical University of Lublin , Lublin , Poland and. 3. c Department of Ophthalmology , Medical University of Bialystok , Bialystok , Poland.
Abstract
PURPOSE: To study the relationship between phacoemulsification-related changes and the baseline parameters of the anterior chamber. SETTING: Military Institute of Medicine, Warsaw, Medical University of Lublin, Medical University of Bialystok. MATERIAL AND METHODS: The study included 228 patients. Anterior chamber depth (ACD), trabecular-iris angle (TIA), central lens thickness (CLT) and axial length of the eye (AXL) were determined prior to and 6 months after surgery. These measurements were used to calculate the ACD(index) describing the degree of postoperative changes in the anterior chamber. K-means clustering, multiple regression and neural networks were used for the analysis. RESULTS: Cataract surgery was reflected by changes in ACD and TIA. The character of changes was described by ACD(index) (p < 0.05). Mean ACD0 was 2.51 ± 0.45 mm and increased to 3.84 ± 0.35 mm (p < 0.05), whereas mean TIA0 was 22.84 ± 7.43° and increased to 30.97 ± 7.99° (p < 0.05). ΔACD and ΔTIA were determined on the basis of baseline parameters defined by ACD(index), characterizing the structural type of the eye. The variability of ACD(index) explained 42.65% of variance in ΔACD and ΔTIA. The quality of network for validation and test samples was from 0.72 to 0.83. CONCLUSIONS: Cataract surgery-related changes in ACD and TIA are determined by the type of the eye. Although the linear model of the relationship between baseline parameters of the eye and their postoperative changes is correct, it does not explain the degree of the latter phenomenon. Preoperative consideration of other parameters characterizing anatomical relationships of the eye would enable the prediction of phacoemulsification-related changes in the anterior segment.
PURPOSE: To study the relationship between phacoemulsification-related changes and the baseline parameters of the anterior chamber. SETTING: Military Institute of Medicine, Warsaw, Medical University of Lublin, Medical University of Bialystok. MATERIAL AND METHODS: The study included 228 patients. Anterior chamber depth (ACD), trabecular-iris angle (TIA), central lens thickness (CLT) and axial length of the eye (AXL) were determined prior to and 6 months after surgery. These measurements were used to calculate the ACD(index) describing the degree of postoperative changes in the anterior chamber. K-means clustering, multiple regression and neural networks were used for the analysis. RESULTS:Cataract surgery was reflected by changes in ACD and TIA. The character of changes was described by ACD(index) (p < 0.05). Mean ACD0 was 2.51 ± 0.45 mm and increased to 3.84 ± 0.35 mm (p < 0.05), whereas mean TIA0 was 22.84 ± 7.43° and increased to 30.97 ± 7.99° (p < 0.05). ΔACD and ΔTIA were determined on the basis of baseline parameters defined by ACD(index), characterizing the structural type of the eye. The variability of ACD(index) explained 42.65% of variance in ΔACD and ΔTIA. The quality of network for validation and test samples was from 0.72 to 0.83. CONCLUSIONS:Cataract surgery-related changes in ACD and TIA are determined by the type of the eye. Although the linear model of the relationship between baseline parameters of the eye and their postoperative changes is correct, it does not explain the degree of the latter phenomenon. Preoperative consideration of other parameters characterizing anatomical relationships of the eye would enable the prediction of phacoemulsification-related changes in the anterior segment.
Entities:
Keywords:
Anterior chamber depth; modeling of the anterior chamber changes; phacoemulsification-related changes; trabecular-iris angle; ultrabiomicroscopic evaluation