| Literature DB >> 25320448 |
Kamal K Pal1, Rinku Dey1, Manesh Thomas1, Sucheta Ghorai1, Dharmesh Sherathia1, Sejal Vanpariya1, Rupal Rupapara1, Priya Rawal1, Mona Mandaliya1, Bhoomika Sukhadiya1, Anil K Saxena2.
Abstract
Haloarchaea are predominant in the salt crystallizers of the Rann of Kutch when the concentration of salts approaches saturation levels. The obligate and extreme halophilic archaeon 3A1-DGR, isolated from a salt crystallizer pond of the Little Rann of Kutch, India, needs minimum of 10 % NaCl in the growth medium. To understand the mechanism(s) of osmotolerance and adaptation at extreme osmolarity, and to mine relevant gene(s), the genome of this haloarchaeon, 3A1-DGR, was sequenced. We report here, the 2.88 Mb draft genome sequence of the haloarchaeon 3A1-DGR, with G+C content of 68 % and the possible involvement of 43 genes in stress tolerance. Further studies of the genome of this haloarchaeon would be required to identify gene(s) that might be responsible for imparting extreme osmotolerance.Entities:
Keywords: Draft whole genome sequencing; Extreme halophile; Haloarchaea; Osmotolerance
Year: 2014 PMID: 25320448 PMCID: PMC4186937 DOI: 10.1007/s12088-014-0483-7
Source DB: PubMed Journal: Indian J Microbiol ISSN: 0046-8991 Impact factor: 2.461