Literature DB >> 25320262

Candida parapsilosis osteomyelitis.

Rekha Lopez1, Alistair Robert Hunter2, Orla Geoghegan3, Elli Demertzi1.   

Abstract

A 51-year-old previously fit and healthy gentleman sustained a circular saw injury to his right thumb with partial amputation and an open multifragmentary fracture of his distal phalanx. He underwent open reduction and internal fixation under the hand surgery team. He developed a postoperative infection discharging pus 2 weeks postoperatively, which later grew Candida parapsilosis. He underwent radical debridement and removal of a K-wire, then a further second debridement 2 days later. Ceftriaxone was started empirically while awaiting cultures. Tissue and bone biopsy samples obtained in theatre all grew C. parapsilosis and he was started on caspofungin for 1 week, and switched on to oral fluconazole to complete a 6-week course. He has progressed well and has regained function in his thumb after 3 months, without any sign of ongoing infection. 2014 BMJ Publishing Group Ltd.

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Year:  2014        PMID: 25320262      PMCID: PMC4202085          DOI: 10.1136/bcr-2014-206520

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  12 in total

1.  Differential activities of newer antifungal agents against Candida albicans and Candida parapsilosis biofilms.

Authors:  Aspasia Katragkou; Athanasios Chatzimoschou; Maria Simitsopoulou; Maria Dalakiouridou; Eudoxia Diza-Mataftsi; Chaido Tsantali; Emmanuel Roilides
Journal:  Antimicrob Agents Chemother       Date:  2007-10-15       Impact factor: 5.191

Review 2.  Two hundred and eleven cases of Candida osteomyelitis: 17 case reports and a review of the literature.

Authors:  Amy K Slenker; Scott W Keith; David L Horn
Journal:  Diagn Microbiol Infect Dis       Date:  2012-05       Impact factor: 2.803

3.  Treatment and outcomes of Candida osteomyelitis: review of 53 cases from the PATH Alliance® registry.

Authors:  D Neofytos; S Huprikar; A Reboli; M Schuster; N Azie; B Franks; D Horn
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2013-08-02       Impact factor: 3.267

4.  Candida parapsilosis spondylodiscitis after lumbar discectomy.

Authors:  Kyungil Cho; Sun-Ho Lee; Eun-Sang Kim; Whan Eoh
Journal:  J Korean Neurosurg Soc       Date:  2010-04-30

Review 5.  Current treatment strategies for disseminated candidiasis.

Authors:  Brad J Spellberg; Scott G Filler; John E Edwards
Journal:  Clin Infect Dis       Date:  2005-12-02       Impact factor: 9.079

6.  Systematic review and meta-analysis of the tolerability and hepatotoxicity of antifungals in empirical and definitive therapy for invasive fungal infection.

Authors:  Jiun-Ling Wang; Chia-Hsuin Chang; Yinong Young-Xu; K Arnold Chan
Journal:  Antimicrob Agents Chemother       Date:  2010-03-22       Impact factor: 5.191

7.  High frequency of Candida parapsilosis on the hands of healthy hosts.

Authors:  L A Bonassoli; M Bertoli; T I E Svidzinski
Journal:  J Hosp Infect       Date:  2005-02       Impact factor: 3.926

Review 8.  Candida parapsilosis, an emerging fungal pathogen.

Authors:  David Trofa; Attila Gácser; Joshua D Nosanchuk
Journal:  Clin Microbiol Rev       Date:  2008-10       Impact factor: 26.132

9.  Antifungal penetration into normal rabbit nucleus pulposus.

Authors:  Jason M Conaughty; Sanjay Khurana; Kresimir Banovac; Octavio V Martinez; Frank J Eismont
Journal:  Spine (Phila Pa 1976)       Date:  2004-07-15       Impact factor: 3.468

10.  Candida osteomyelitis: analysis of 207 pediatric and adult cases (1970-2011).

Authors:  Maria N Gamaletsou; Dimitrios P Kontoyiannis; Nikolaos V Sipsas; Brad Moriyama; Elizabeth Alexander; Emmanuel Roilides; Barry Brause; Thomas J Walsh
Journal:  Clin Infect Dis       Date:  2012-08-21       Impact factor: 9.079

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