Literature DB >> 20461172

Candida parapsilosis spondylodiscitis after lumbar discectomy.

Kyungil Cho1, Sun-Ho Lee, Eun-Sang Kim, Whan Eoh.   

Abstract

Candida is a relatively rare cause of spinal infections that commonly affects immunocompromised patients. A 70-year-old woman, who underwent a lumbar discectomy on L5-S1 two months earlier, was admitted to our department complaining of persistent back and leg pain. Magnetic resonance imaging showed irregular enhancing mass lesion in L5-S1 intervertebral space, suggest of pyogenic discitis with epidural abscess. The surgery was performed via retroperitoneal approach and the infected material at L5-S1 intervertebral space was removed. The histological examination of the specimen revealed chronic inflammation involving the bone and soft tissue, and a culture of the excised material was positive for Candida parapsilosis. The patient received intravenous fluconazole for 4 weeks after surgery and oral fluconazole 400 mg/day for 3 months after surgery. The patient made a full recovery with no symptoms 6 months after surgery. We present a rare case of spondylodiscitis after a lumbar discectomy due to Candida parapsilosis and discuss treatment option with a review of the literatures.

Entities:  

Keywords:  Candida; Fungal infection; Osteomyelitis; Spondylodiscitis; Vertebra

Year:  2010        PMID: 20461172      PMCID: PMC2864824          DOI: 10.3340/jkns.2010.47.4.295

Source DB:  PubMed          Journal:  J Korean Neurosurg Soc        ISSN: 1225-8245


  17 in total

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Journal:  Can J Surg       Date:  1989-05       Impact factor: 2.089

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Authors:  Rabi M Khazim; Ujjwal K Debnath; Youssef Fares
Journal:  Eur Spine J       Date:  2006-01-21       Impact factor: 3.134

4.  Nosocomial bloodstream infections in United States hospitals: a three-year analysis.

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Journal:  Clin Infect Dis       Date:  1999-08       Impact factor: 9.079

5.  Spondylodiscitis and epidural abscess due to Candida albicans.

Authors:  P Derkinderen; F Bruneel; O Bouchaud; B Regnier
Journal:  Eur Spine J       Date:  2000-02       Impact factor: 3.134

6.  Diagnosis and treatment of Candida vertebral osteomyelitis: clinical experience with a short course therapy of amphotericin B lipid complex.

Authors:  Lawrence A Cone; Richard G Byrd; Barbara E Potts; Moxell Wuesthoff
Journal:  Surg Neurol       Date:  2004-09

7.  Hematogenous Candida vertebral osteomyelitis treated with ketoconazole.

Authors:  B A Dijkmans; M I Koolen; R P Mouton; T H Falke; P J van den Broek; J W van der Meer
Journal:  Infection       Date:  1982 Sep-Oct       Impact factor: 3.553

8.  Cervical spondylodiscitis caused by Candida albicans in non-immunocompromised patient.

Authors:  Hyung Ho Moon; Jae Hoon Kim; Byung Gwan Moon; Joo Seung Kim
Journal:  J Korean Neurosurg Soc       Date:  2008-01-20

9.  Vertebral disc space infection and osteomyelitis due to Candida albicans in a patient with acute myelomonocytic leukemia.

Authors:  B S Shaikh; P C Appelbaum; R C Aber
Journal:  Cancer       Date:  1980-03-01       Impact factor: 6.860

10.  Candida albicans osteomyelitis of the cervical spine.

Authors:  Jang-Gyu Cha; Hyun-Sook Hong; Yoon-Woo Koh; Hee-Kyung Kim; Jung-Mi Park
Journal:  Skeletal Radiol       Date:  2008-02-02       Impact factor: 2.199

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  5 in total

1.  Candida parapsilosis osteomyelitis.

Authors:  Rekha Lopez; Alistair Robert Hunter; Orla Geoghegan; Elli Demertzi
Journal:  BMJ Case Rep       Date:  2014-10-15

2.  Candidal Vertebral Osteomyelitis in the Midst of Renal Disorders.

Authors:  Anusha Gopinathan; Anil Kumar; Srivatsa Nagaraja Rao; Krishna Kumar; Shamsul Karim
Journal:  J Clin Diagn Res       Date:  2016-04-01

3.  A rare case of Candida parapsilosis osteomyelitis: a literature review and proposed treatment algorithm.

Authors:  John Michael Yingling; Li Sun; Richard Yoon; Frank Liporace
Journal:  Patient Saf Surg       Date:  2017-12-21

4.  Extreme Lateral Interbody Fusion Complicated by Fungal Osteomyelitis: Case Report and Quick Review of the Literature.

Authors:  Ronen Blecher; Emre Yilmaz; Marc Moisi; Rod J Oskouian; Jens Chapman
Journal:  Cureus       Date:  2018-05-31

5.  Candida Spondylitis Considered as Microbial Substitution After Multiple Surgeries for Postoperative Lumbar Spine Infection.

Authors:  Yusuke Eda; Toru Funayama; Masaki Tatsumura; Masao Koda; Masashi Yamazaki
Journal:  Cureus       Date:  2021-05-12
  5 in total

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