Literature DB >> 25318059

A free-radical cascade methylation/cyclization of N-arylacrylamides and isocyanides with dicumyl peroxide.

Zhengbao Xu1, Chaoxian Yan, Zhong-Quan Liu.   

Abstract

A free-radical cascade methylation/cyclization of a wide range of N-arylacrylamides and isocyanides is demonstrated by using dicumyl peroxide as the methylating reagent, which provides a convenient and selective access to various methylated N-heterocycles such as oxindoles and phenanthridines.

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Year:  2014        PMID: 25318059     DOI: 10.1021/ol502738a

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  3 in total

1.  Crystal structure of (E)-4-benzyl-idene-6-phenyl-1,2,3,4,7,8,9,10-octa-hydro-phenanthridine.

Authors:  Baidaa K Al-Rubaye; Alice Brink; Gary J Miller; Herman Potgieter; Mohamad J Al-Jeboori
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2017-06-30

2.  Copper-catalyzed methylative difunctionalization of alkenes.

Authors:  Xu Bao; Takayuki Yokoe; Tu M Ha; Qian Wang; Jieping Zhu
Journal:  Nat Commun       Date:  2018-09-13       Impact factor: 14.919

3.  Metal-free oxidative isocyanides insertion with aromatic aldehydes to aroylated N-heterocycles.

Authors:  Yimiao He; Xuelian Wang; Jun-An Xiao; Jinying Pang; Chunfang Gan; Yanmin Huang; Chusheng Huang
Journal:  RSC Adv       Date:  2018-01-15       Impact factor: 3.361

  3 in total

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