| Literature DB >> 25314073 |
Sivakanthan Kasinathan1, Steven Henikoff2.
Abstract
In this issue of Cancer Cell, Yang et al. describe a causal relationship between gene body methylation and gene expression and a role for genic methylation in response to clinical DNA methylation inhibitors, which suggests that the mechanism of action of these inhibitors includes gene body hypomethylation-induced downregulation of cancer-associated genes.Entities:
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Year: 2014 PMID： 25314073 PMCID： PMC4322907 DOI： 10.1016/j.ccell.2014.09.004
Source DB: PubMed Journal: Cancer Cell ISSN： 1535-6108 Impact factor: 31.743