Literature DB >> 2531281

Integrity of the exon 6 sequence is essential for tissue-specific alternative splicing of human leukocyte common antigen pre-mRNA.

A Y Tsai1, M Streuli, H Saito.   

Abstract

By alternative splicing, exons 4, 5, and 6 of the human leukocyte common antigen (LCA) gene are included in B-cell mRNA but excluded from thymocyte mRNA. A mini-LCA gene that contains only LCA exons 2, 6, and 8 faithfully reproduces this tissue-specific alternative splicing in mouse B and thymocyte cell lines. Elimination of almost all of the intron sequences associated with exon 6 had no effect on the alternative splicing, while linker-scanning analysis showed that a significant length of the exon 6 sequence is essential for alternative splicing.

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Year:  1989        PMID： 2531281      PMCID： PMC362542          DOI： 10.1128/mcb.9.10.4550-4555.1989

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  29 in total

1.  The isolation and characterization of the human helper inducer T cell subset.

Authors:  C Morimoto; N L Letvin; A W Boyd; M Hagan; H M Brown; M M Kornacki; S F Schlossman
Journal:  J Immunol       Date:  1985-06       Impact factor: 5.422

2.  Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

Authors:  A N Akbar; L Terry; A Timms; P C Beverley; G Janossy
Journal:  J Immunol       Date:  1988-04-01       Impact factor: 5.422

3.  Unusual splice sites revealed by mutagenic inactivation of an authentic splice site of the rabbit beta-globin gene.

Authors:  B Wieringa; F Meyer; J Reiser; C Weissmann
Journal:  Nature       Date:  1983-01-06       Impact factor: 49.962

4.  The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase.

Authors:  H Charbonneau; N K Tonks; K A Walsh; E H Fischer
Journal:  Proc Natl Acad Sci U S A       Date:  1988-10       Impact factor: 11.205

5.  The isolation and characterization of the human suppressor inducer T cell subset.

Authors:  C Morimoto; N L Letvin; J A Distaso; W R Aldrich; S F Schlossman
Journal:  J Immunol       Date:  1985-03       Impact factor: 5.422

6.  Organization of the Ly-5 gene.

Authors:  Y Saga; J S Tung; F W Shen; T C Pancoast; E A Boyse
Journal:  Mol Cell Biol       Date:  1988-11       Impact factor: 4.272

7.  Characterization of CD45 and CD45R monoclonal antibodies using transfected mouse cell lines that express individual human leukocyte common antigens.

Authors:  M Streuli; C Morimoto; M Schrieber; S F Schlossman; H Saito
Journal:  J Immunol       Date:  1988-12-01       Impact factor: 5.422

8.  Complete exon-intron organization of the human leukocyte common antigen (CD45) gene.

Authors:  L R Hall; M Streuli; S F Schlossman; H Saito
Journal:  J Immunol       Date:  1988-10-15       Impact factor: 5.422

9.  A new member of the immunoglobulin superfamily that has a cytoplasmic region homologous to the leukocyte common antigen.

Authors:  M Streuli; N X Krueger; L R Hall; S F Schlossman; H Saito
Journal:  J Exp Med       Date:  1988-11-01       Impact factor: 14.307

10.  Human homologue of murine T200 glycoprotein.

Authors:  M B Omary; I S Trowbridge; H A Battifora
Journal:  J Exp Med       Date:  1980-10-01       Impact factor: 14.307
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  15 in total

1.  A model system for activation-induced alternative splicing of CD45 pre-mRNA in T cells implicates protein kinase C and Ras.

Authors:  K W Lynch; A Weiss
Journal:  Mol Cell Biol       Date:  2000-01       Impact factor: 4.272

2.  PTPRC (CD45) C77G mutation does not contribute to multiple sclerosis susceptibility in Sardinian patients.

Authors:  Eleonora Cocco; Maria Rita Murru; Cristina Melis; Lucia Schirru; Elisabetta Solla; Marina Lai; Marcella Rolesu; Maria Giovanna Marrosu
Journal:  J Neurol       Date:  2004-09       Impact factor: 4.849

3.  Identification of a specific exon sequence that is a major determinant in the selection between a natural and a cryptic 5' splice site.

Authors:  L Domenjoud; H Gallinaro; L Kister; S Meyer; M Jacob
Journal:  Mol Cell Biol       Date:  1991-09       Impact factor: 4.272

4.  Exon as well as intron sequences are cis-regulating elements for the mutually exclusive alternative splicing of the beta tropomyosin gene.

Authors:  D Libri; M Goux-Pelletan; E Brody; M Y Fiszman
Journal:  Mol Cell Biol       Date:  1990-10       Impact factor: 4.272

5.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1990-01-11       Impact factor: 16.971

6.  In vivo recognition of a vertebrate mini-exon as an exon-intron-exon unit.

Authors:  D A Sterner; S M Berget
Journal:  Mol Cell Biol       Date:  1993-05       Impact factor: 4.272

7.  Selection of novel exon recognition elements from a pool of random sequences.

Authors:  H Tian; R Kole
Journal:  Mol Cell Biol       Date:  1995-11       Impact factor: 4.272

8.  Elements regulating an alternatively spliced exon of the rat fibronectin gene.

Authors:  G S Huh; R O Hynes
Journal:  Mol Cell Biol       Date:  1993-09       Impact factor: 4.272

9.  Presence of negative and positive cis-acting RNA splicing elements within and flanking the first tat coding exon of human immunodeficiency virus type 1.

Authors:  B A Amendt; D Hesslein; L J Chang; C M Stoltzfus
Journal:  Mol Cell Biol       Date:  1994-06       Impact factor: 4.272

10.  Mutations which alter splicing in the human hypoxanthine-guanine phosphoribosyltransferase gene.

Authors:  H Steingrimsdottir; G Rowley; G Dorado; J Cole; A R Lehmann
Journal:  Nucleic Acids Res       Date:  1992-03-25       Impact factor: 16.971
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