Literature DB >> 25295940

Genome editing: a tool for research and therapy: towards a functional understanding of variants for molecular diagnostics using genome editing.

Shengdar Q Tsai1, A John Iafrate1, J Keith Joung1.   

Abstract

Mesh：

Year:  2014        PMID： 25295940     DOI： 10.1038/nm.3722

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  12 in total

1.  Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm.

Authors:  Prateek Kumar; Steven Henikoff; Pauline C Ng
Journal:  Nat Protoc       Date:  2009-06-25       Impact factor: 13.491

Review 2.  Standardized decision support in next generation sequencing reports of somatic cancer variants.

Authors:  Rodrigo Dienstmann; Fei Dong; Darrell Borger; Dora Dias-Santagata; Leif W Ellisen; Long P Le; A John Iafrate
Journal:  Mol Oncol       Date:  2014-04-04       Impact factor: 6.603

Review 3.  CRISPR-Cas systems for editing, regulating and targeting genomes.

Authors:  Jeffry D Sander; J Keith Joung
Journal:  Nat Biotechnol       Date:  2014-03-02       Impact factor: 54.908

4.  Progress and challenges in genome-wide association studies in humans.

Authors:  Peter Donnelly
Journal:  Nature       Date:  2008-12-11       Impact factor: 49.962

5.  A method and server for predicting damaging missense mutations.

Authors:  Ivan A Adzhubei; Steffen Schmidt; Leonid Peshkin; Vasily E Ramensky; Anna Gerasimova; Peer Bork; Alexey S Kondrashov; Shamil R Sunyaev
Journal:  Nat Methods       Date:  2010-04       Impact factor: 28.547

6.  One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering.

Authors:  Haoyi Wang; Hui Yang; Chikdu S Shivalila; Meelad M Dawlaty; Albert W Cheng; Feng Zhang; Rudolf Jaenisch
Journal:  Cell       Date:  2013-05-02       Impact factor: 41.582

7.  High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells.

Authors:  Yanfang Fu; Jennifer A Foden; Cyd Khayter; Morgan L Maeder; Deepak Reyon; J Keith Joung; Jeffry D Sander
Journal:  Nat Biotechnol       Date:  2013-06-23       Impact factor: 54.908

8.  Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing.

Authors:  Dirk Heckl; Monika S Kowalczyk; David Yudovich; Roger Belizaire; Rishi V Puram; Marie E McConkey; Anne Thielke; Jon C Aster; Aviv Regev; Benjamin L Ebert
Journal:  Nat Biotechnol       Date:  2014-06-22       Impact factor: 54.908

9.  Optimized cell transplantation using adult rag2 mutant zebrafish.

Authors:  Qin Tang; Nouran S Abdelfattah; Jessica S Blackburn; John C Moore; Sarah A Martinez; Finola E Moore; Riadh Lobbardi; Inês M Tenente; Myron S Ignatius; Jason N Berman; Robert S Liwski; Yariv Houvras; David M Langenau
Journal:  Nat Methods       Date:  2014-07-20       Impact factor: 28.547

10.  Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing.

Authors:  Shengdar Q Tsai; Nicolas Wyvekens; Cyd Khayter; Jennifer A Foden; Vishal Thapar; Deepak Reyon; Mathew J Goodwin; Martin J Aryee; J Keith Joung
Journal:  Nat Biotechnol       Date:  2014-04-25       Impact factor: 54.908
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  3 in total

1.  Genome editing technologies: defining a path to clinic.

Authors:  Jacqueline Corrigan-Curay; Marina O'Reilly; Donald B Kohn; Paula M Cannon; Gang Bao; Frederic D Bushman; Dana Carroll; Toni Cathomen; J Keith Joung; David Roth; Michel Sadelain; Andrew M Scharenberg; Christof von Kalle; Feng Zhang; Robert Jambou; Eugene Rosenthal; Morad Hassani; Aparna Singh; Matthew H Porteus
Journal:  Mol Ther       Date:  2015-05       Impact factor: 11.454

2.  The post-genomic era of biological network alignment.

Authors:  Fazle E Faisal; Lei Meng; Joseph Crawford; Tijana Milenković
Journal:  EURASIP J Bioinform Syst Biol       Date:  2015-06-04

3.  WU-CRISPR: characteristics of functional guide RNAs for the CRISPR/Cas9 system.

Authors:  Nathan Wong; Weijun Liu; Xiaowei Wang
Journal:  Genome Biol       Date:  2015-11-02       Impact factor: 13.583
  3 in total

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