Literature DB >> 25289537

Molecular mechanisms in tumor-cell killing by activated macrophages.

D O Adams1, C F Nathan2.   

Abstract

Macrophages kill tumor cells with and without the aid of antibody and evidence suggests that secreted cytotoxic substances are at work in each system. Here Dolph Adams and Carl Nathan discuss the likely involvement in both pathways of several such substances including cytolytic protease and hydrogen peroxide.
Copyright © 1983. Published by Elsevier B.V.

Entities:  

Year:  1983        PMID： 25289537     DOI： 10.1016/0167-5699(83)90005-1

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  11 in total

1.  Production of TNF-alpha, IL-1beta, IL-12 and IFN-gamma in murine peritoneal macrophages on treatment with wheat germ agglutinin in vitro: involvement of tyrosine kinase pathways.

Authors:  Ajit Sodhi; Varun Kesherwani
Journal:  Glycoconj J       Date:  2007-08-01       Impact factor: 2.916

Review 2.  Cytotoxic effector cells of the immune system.

Authors:  P Groscurth
Journal:  Anat Embryol (Berl)       Date:  1989

3.  Tuftsin induced tumor necrosis activity.

Authors:  M S Wleklik; M Luczak; V A Najjar
Journal:  Mol Cell Biochem       Date:  1987-06       Impact factor: 3.396

4.  TNF-alpha mediated selection of macrophage-resistant gene-regulatory tumor variants.

Authors:  L Remels; A Neirynck; L Brys; E Vercauteren; P De Baetselier
Journal:  Clin Exp Metastasis       Date:  1989 Sep-Oct       Impact factor: 5.150

5.  Dynamics of actin filaments in microglia during Fc receptor-mediated phagocytosis.

Authors:  E M Abd-el-Basset; S Fedoroff
Journal:  Acta Neuropathol       Date:  1994       Impact factor: 17.088

Review 6.  Effects of tumor growth on host defenses.

Authors:  G J Cianciolo; R Snyderman
Journal:  Cancer Metastasis Rev       Date:  1986       Impact factor: 9.264

7.  Enhanced killing capacity of human Kupffer cells after activation with human granulocyte/macrophage-colony-stimulating factor and interferon gamma.

Authors:  B Schuurman; G Heuff; R H Beelen; S Meyer
Journal:  Cancer Immunol Immunother       Date:  1994-09       Impact factor: 6.968

8.  Defective interleukin-1 production by monocytes from patients with malignant disease. Interferon increases IL-1 production.

Authors:  J Herman; M C Kew; A R Rabson
Journal:  Cancer Immunol Immunother       Date:  1984       Impact factor: 6.968

9.  A phase I pharmacokinetic study of recombinant human tumor necrosis factor administered by a 5-day continuous infusion.

Authors:  A Mittelman; C Puccio; E Gafney; N Coombe; B Singh; D Wood; P Nadler; T Ahmed; Z Arlin
Journal:  Invest New Drugs       Date:  1992-08       Impact factor: 3.850

10.  The role of phospholipases from inflammatory macrophages in demyelination.

Authors:  J Trotter; M E Smith
Journal:  Neurochem Res       Date:  1986-03       Impact factor: 3.996
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