Literature DB >> 25288177

Statins, glycemia, and diabetes mellitus: another point of view.

Tomáš Stulc1, Richard Ceška.   

Abstract

Glycemic effects of statins have recently become a topic of heated debate. On closer inspection, however, the prevailing opinion regarding this issue may prove to be unsubstantiated. We suggest that the harmful effect of statin-induced diabetes is likely overestimated, and the consequences of the glycemic effects of statins may, theoretically, apply to a greater number of patients beyond just those with statin-induced diabetes. Most notably, though, careful consideration of the issue suggests, albeit surprisingly, that the clinical implications of the glycemic effects of statins may actually be rather limited.

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Year:  2014        PMID: 25288177     DOI: 10.1007/s11883-014-0458-5

Source DB:  PubMed          Journal:  Curr Atheroscler Rep        ISSN: 1523-3804            Impact factor:   5.113


  16 in total

Review 1.  The use of statins in people at risk of developing diabetes mellitus: evidence and guidance for clinical practice.

Authors:  Naveed A Sattar; Henry Ginsberg; Kausik Ray; M John Chapman; Marcello Arca; Maurizio Averna; D John Betteridge; Deepak Bhatnagar; Elena Bilianou; Rafael Carmena; Richard Ceška; Alberto Corsini; Raimund Erbel; Paul D Flynn; Xavier Garcia-Moll; Janusz Gumprecht; Shun Ishibashi; Selim Jambart; John J P Kastelein; Vincent Maher; Pedro Marques da Silva; Luis Masana; Masato Odawara; Terje R Pedersen; Carlo Maria Rotella; Ibrahim Salti; Tamio Teramoto; Lale Tokgozoglu; Peter P Toth; Paul Valensi; Bruno Vergès
Journal:  Atheroscler Suppl       Date:  2014-06       Impact factor: 3.235

2.  Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: a meta-analysis.

Authors:  David Preiss; Sreenivasa Rao Kondapally Seshasai; Paul Welsh; Sabina A Murphy; Jennifer E Ho; David D Waters; David A DeMicco; Philip Barter; Christopher P Cannon; Marc S Sabatine; Eugene Braunwald; John J P Kastelein; James A de Lemos; Michael A Blazing; Terje R Pedersen; Matti J Tikkanen; Naveed Sattar; Kausik K Ray
Journal:  JAMA       Date:  2011-06-22       Impact factor: 56.272

3.  Impact of diabetes on cardiovascular disease risk and all-cause mortality in older men: influence of age at onset, diabetes duration, and established and novel risk factors.

Authors:  S Goya Wannamethee; A Gerald Shaper; Peter H Whincup; Lucy Lennon; Naveed Sattar
Journal:  Arch Intern Med       Date:  2011-03-14

4.  Deterioration of glucose homeostasis in type 2 diabetic patients one year after beginning of statins therapy.

Authors:  Alfonso Bellia; Stefano Rizza; Marco Felice Lombardo; Giulia Donadel; Rossella Fabiano; Katia Andreadi; Michael J Quon; Paolo Sbraccia; Massimo Federici; Manfredi Tesauro; Carmine Cardillo; Davide Lauro
Journal:  Atherosclerosis       Date:  2012-05-08       Impact factor: 5.162

5.  Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials.

Authors:  Naveed Sattar; David Preiss; Heather M Murray; Paul Welsh; Brendan M Buckley; Anton J M de Craen; Sreenivasa Rao Kondapally Seshasai; John J McMurray; Dilys J Freeman; J Wouter Jukema; Peter W Macfarlane; Chris J Packard; David J Stott; Rudi G Westendorp; James Shepherd; Barry R Davis; Sara L Pressel; Roberto Marchioli; Rosa Maria Marfisi; Aldo P Maggioni; Luigi Tavazzi; Gianni Tognoni; John Kjekshus; Terje R Pedersen; Thomas J Cook; Antonio M Gotto; Michael B Clearfield; John R Downs; Haruo Nakamura; Yasuo Ohashi; Kyoichi Mizuno; Kausik K Ray; Ian Ford
Journal:  Lancet       Date:  2010-02-16       Impact factor: 79.321

6.  Meta-analysis: glycosylated hemoglobin and cardiovascular disease in diabetes mellitus.

Authors:  Elizabeth Selvin; Spyridon Marinopoulos; Gail Berkenblit; Tejal Rami; Frederick L Brancati; Neil R Powe; Sherita Hill Golden
Journal:  Ann Intern Med       Date:  2004-09-21       Impact factor: 25.391

7.  Effect of statins on fasting plasma glucose in diabetic and nondiabetic patients.

Authors:  Rishi Sukhija; Sastry Prayaga; Mohammad Marashdeh; Zoran Bursac; Priyanka Kakar; Darpan Bansal; Rajesh Sachdeva; Sree Hari Kesan; Jawahar L Mehta
Journal:  J Investig Med       Date:  2009-03       Impact factor: 2.895

Review 8.  Markers of dysglycaemia and risk of coronary heart disease in people without diabetes: Reykjavik prospective study and systematic review.

Authors:  Nadeem Sarwar; Thor Aspelund; Gudny Eiriksdottir; Reeta Gobin; Sreenivasa Rao Kondapally Seshasai; Nita G Forouhi; Gunnar Sigurdsson; John Danesh; Vilmundur Gudnason
Journal:  PLoS Med       Date:  2010-05-25       Impact factor: 11.069

9.  Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies.

Authors:  N Sarwar; P Gao; S R Kondapally Seshasai; R Gobin; S Kaptoge; E Di Angelantonio; E Ingelsson; D A Lawlor; E Selvin; M Stampfer; C D A Stehouwer; S Lewington; L Pennells; A Thompson; N Sattar; I R White; K K Ray; J Danesh
Journal:  Lancet       Date:  2010-06-26       Impact factor: 202.731

10.  Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials.

Authors:  C Baigent; L Blackwell; J Emberson; L E Holland; C Reith; N Bhala; R Peto; E H Barnes; A Keech; J Simes; R Collins
Journal:  Lancet       Date:  2010-11-08       Impact factor: 79.321

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  1 in total

Review 1.  Statin Intolerance: the Clinician's Perspective.

Authors:  Tomáš Stulc; Richard Ceška; Antonio M Gotto
Journal:  Curr Atheroscler Rep       Date:  2015-12       Impact factor: 5.113

  1 in total

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