Literature DB >> 25282450

[Two pediatric cases of anti-NMDA receptor antibody encephalitis].

M Ben Azoun1, S Tatencloux2, K Deiva2, P Blanc3.   

Abstract

Although less frequent than viral encephalitis, anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a frequent form of acute pediatric encephalitis. After a prodromal phase of flu-like symptoms, psychiatric symptoms predominate - agitation, anxiety, hallucinations - and can make correct diagnosis more difficult. Also noted are abnormal dyskinesia and dystonia-like movements, partial seizures, difficulties talking or memorizing, and autonomic manifestations. The presentation of two cases of anti-NMDAR encephalitis illustrates the symptoms of this disease. Although the CSF abnormalities are not highly specific of this disease, and MRI most often normal, EEG shows more specific signs. These observations enable us to discuss different treatment options and understand the progression of this disease.
Copyright © 2014 Elsevier Masson SAS. All rights reserved.

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Year:  2014        PMID: 25282450     DOI: 10.1016/j.arcped.2014.08.020

Source DB:  PubMed          Journal:  Arch Pediatr        ISSN: 0929-693X            Impact factor:   1.180


  1 in total

Review 1.  Bilateral symmetrical basal ganglia and thalamic lesions in children: an update (2015).

Authors:  Giulio Zuccoli; Michael Paul Yannes; Raffaele Nardone; Ariel Bailey; Amy Goldstein
Journal:  Neuroradiology       Date:  2015-07-31       Impact factor: 2.804

  1 in total

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