Literature DB >> 25277371

Surgical removal of retroperitoneal tumors after chemotherapy treated testicular tumors.

Allen Sim1, Stefan Aufderklamm, Omar Halalsheh, Tilman Todenhöfer, Christian Schwentner.   

Abstract

In the era of chemotherapy, patients with advanced testicular tumor often presents with residual mass after completion of chemotherapy. Post chemotherapy RPLND is an important part of the multimodality treatment in these patients. According to current guidelines and recommendations, post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND) is recommended in NSGCT patients with all residual lesions and normalized tumor markers. In seminomas, surgery is considered in patients with residual tumor > 3 cm and a positive positron emission tomography (PET) scan. A conventional bilateral template should be performed for patients undergoing PC-RPLND. However, a modified template can be performed in select patients with low volume disease to reduce the long-term morbidities and peri-operative complications. Laparoscopic PC-RPLND is safe and feasible. The oncological outcome of PC-RPLND is excellent if all tumors are resected. PC-RPLND is a complex surgery and should be done in high volume tertiary centers.

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Year:  2014        PMID: 25277371     DOI: 10.1007/s11934-014-0456-8

Source DB:  PubMed          Journal:  Curr Urol Rep        ISSN: 1527-2737            Impact factor:   3.092


  23 in total

1.  Laparoscopic retroperitoneal lymph node dissection: description of the nerve-sparing technique.

Authors:  Reinhard Peschel; Matthew T Gettman; Richard Neururer; Alfred Hobisch; Georg Bartsch
Journal:  Urology       Date:  2002-08       Impact factor: 2.649

Review 2.  Laparoscopic retroperitoneal lymph node dissection: current concepts and limitations.

Authors:  Hannes Steiner; Reinhard Peschel; Georg Bartsch
Journal:  BJU Int       Date:  2009-11       Impact factor: 5.588

3.  Outcome analysis for patients with elevated serum tumor markers at postchemotherapy retroperitoneal lymph node dissection.

Authors:  Stephen D W Beck; Richard S Foster; Richard Bihrle; Lawrence H Einhorn; John P Donohue
Journal:  J Clin Oncol       Date:  2005-09-01       Impact factor: 44.544

4.  [Assessment of residual tumours after systemic treatment of metastatic seminoma: ¹⁸F-2-fluoro-2-deoxy-D-glucose positron emission tomography - meta-analysis of diagnostic value].

Authors:  J Müller; A J Schrader; F Jentzmik; M Schrader
Journal:  Urologe A       Date:  2011-03       Impact factor: 0.639

5.  Complications of post-chemotherapy retroperitoneal lymph node dissection for testis cancer.

Authors:  Ashraf A Mosharafa; Richard S Foster; Michael O Koch; Richard Bihrle; John P Donohue
Journal:  J Urol       Date:  2004-05       Impact factor: 7.450

6.  Is post-chemotherapy resection of seminomatous elements associated with higher acute morbidity?

Authors:  Ashraf A Mosharafa; Richard S Foster; Bradley C Leibovich; Richard Bihrle; Cynthia Johnson; John P Donohue
Journal:  J Urol       Date:  2003-06       Impact factor: 7.450

7.  Is full bilateral retroperitoneal lymph node dissection always necessary for postchemotherapy residual tumor?

Authors:  Stephen D W Beck; Richard S Foster; Richard Bihrle; John P Donohue; Lawrence H Einhorn
Journal:  Cancer       Date:  2007-09-15       Impact factor: 6.860

8.  Incidence of metastatic nonseminomatous germ cell tumor outside the boundaries of a modified postchemotherapy retroperitoneal lymph node dissection.

Authors:  Brett S Carver; Bobby Shayegan; Scott Eggener; Jason Stasi; Robert J Motzer; George J Bosl; Joel Sheinfeld
Journal:  J Clin Oncol       Date:  2007-10-01       Impact factor: 44.544

9.  2-18fluoro-deoxy-D-glucose positron emission tomography is a reliable predictor for viable tumor in postchemotherapy seminoma: an update of the prospective multicentric SEMPET trial.

Authors:  Maria De Santis; Alexander Becherer; Carsten Bokemeyer; Franz Stoiber; Karin Oechsle; Franz Sellner; Alois Lang; Kurt Kletter; Bernhard M Dohmen; Christian Dittrich; Jörg Pont
Journal:  J Clin Oncol       Date:  2004-03-15       Impact factor: 44.544

10.  Preservation of ejaculation in patients undergoing nerve-sparing postchemotherapy retroperitoneal lymph node dissection for metastatic testicular cancer.

Authors:  Joseph A Pettus; Brett S Carver; Timothy Masterson; Jason Stasi; Joel Sheinfeld
Journal:  Urology       Date:  2008-11-20       Impact factor: 2.649

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