Literature DB >> 25269132

Stellate ganglion block used to treat symptoms associated with combat-related post-traumatic stress disorder: a case series of 166 patients.

Sean W Mulvaney1, James H Lynch2, Matthew J Hickey3, Tabassum Rahman-Rawlins3, Matthew Schroeder1, Shawn Kane4, Eugene Lipov5.   

Abstract

OBJECTIVE: Report the successful use of stellate ganglion blocks (SGBs) in 166 active duty service members with multiple combat deployments experiencing anxiety symptoms associated with post-traumatic stress disorder (PTSD).
BACKGROUND: Successful treatment of PTSD symptoms with SGB has been reported previously. This is the largest published case series evaluating SGB with a minimum of 3 months follow-up.
METHODS: Following clinical interview including administration of the PTSD Checklist (PCL), 166 service members with symptoms of PTSD elected to receive a SGB. All patients received a SGB on the right side at the level of the sixth cervical vertebrae (C6). The PCL was administered the day before treatment to establish a baseline, repeated 1 week later, and then monthly out to 3 months. A positive response was considered to be an improvement in the PCL score by 10 or greater points. Follow-up PCL scores from 3 to 6 months were obtained and analyzed for 166 patients.
RESULTS: In a military population with multiple combat deployments, over 70% of the patients treated had a clinically significant improvement in their PCL score which persisted beyond 3 to 6 months postprocedure.
CONCLUSION: Selective blockade of the right cervical sympathetic chain at the C6 level is a safe and minimally invasive procedure that may provide durable relief from anxiety symptoms associated with PTSD. Reprint &
Copyright © 2014 Association of Military Surgeons of the U.S.

Entities:  

Mesh:

Substances:

Year:  2014        PMID: 25269132     DOI: 10.7205/MILMED-D-14-00151

Source DB:  PubMed          Journal:  Mil Med        ISSN: 0026-4075            Impact factor:   1.437


  15 in total

Review 1.  Possible Reversal of PTSD-Related DNA Methylation by Sympathetic Blockade.

Authors:  Eugene G Lipov; Kenneth Candido; Elspeth C Ritchie
Journal:  J Mol Neurosci       Date:  2017-03-31       Impact factor: 3.444

Review 2.  A review of the use of stellate ganglion block in the treatment of PTSD.

Authors:  Eugene Lipov; Elspeth Cameron Ritchie
Journal:  Curr Psychiatry Rep       Date:  2015-08       Impact factor: 5.285

3.  Safety and Patient Acceptability of Stellate Ganglion Blockade as a Treatment Adjunct for Combat-Related Post-Traumatic Stress Disorder: A Quality Assurance Initiative.

Authors:  Brian McLean
Journal:  Cureus       Date:  2015-09-10

4.  Efficacy and safety of stellate ganglion block in chronic ulcerative colitis.

Authors:  Eugene Lipov; Ken Candido
Journal:  World J Gastroenterol       Date:  2017-05-07       Impact factor: 5.742

5.  Efficacy and safety of stellate ganglion block in chronic ulcerative colitis.

Authors:  Hong-Ying Zhao; Guo-Tao Yang; Ning-Ning Sun; Yu Kong; Yun-Feng Liu
Journal:  World J Gastroenterol       Date:  2017-01-21       Impact factor: 5.742

6.  Transition from Deep Regional Blocks toward Deep Nerve Hydrodissection in the Upper Body and Torso: Method Description and Results from a Retrospective Chart Review of the Analgesic Effect of 5% Dextrose Water as the Primary Hydrodissection Injectate to Enhance Safety.

Authors:  Stanley K H Lam; Kenneth Dean Reeves; An-Lin Cheng
Journal:  Biomed Res Int       Date:  2017-10-01       Impact factor: 3.411

7.  Case Series: Cancer-Related Facial Pain Treated with Stellate Ganglion Block.

Authors:  Raheleh Rahimi Darabad; Jerry P Kalangara; Anna Woodbury
Journal:  Palliat Med Rep       Date:  2020-12-02

8.  Case control study: hyperbaric oxygen treatment of mild traumatic brain injury persistent post-concussion syndrome and post-traumatic stress disorder.

Authors:  Paul G Harch; Susan R Andrews; Edward F Fogarty; Juliette Lucarini; Keith W Van Meter
Journal:  Med Gas Res       Date:  2017-10-17

9.  Stellate ganglion block attenuates chronic stress induced depression in rats.

Authors:  Weiwei Wang; Weidong Shi; Hua Qian; Xijin Deng; Tong Wang; Wenzhi Li
Journal:  PLoS One       Date:  2017-08-31       Impact factor: 3.240

10.  Behavioral health clinicians endorse stellate ganglion block as a valuable intervention in the treatment of trauma-related disorders.

Authors:  James H Lynch; Peter D Muench; John C Okiishi; Gary E Means; Sean W Mulvaney
Journal:  J Investig Med       Date:  2021-03-16       Impact factor: 2.895

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.