Literature DB >> 26073361

A review of the use of stellate ganglion block in the treatment of PTSD.

Eugene Lipov1, Elspeth Cameron Ritchie.   

Abstract

Current treatments for PTSD are often not effective or acceptable to the patient. There are a number of emerging new treatments. One promising new one is stellate ganglion block, an anesthetic treatment for pain which relieves symptoms of severe and chronic PTSD in some patients. The focus of this chapter is to summarize clinical evidence available for the effectiveness of cervical sympathetic ganglion injection called stellate ganglion block (SGB), as well as demonstrate possible clinical applications of its use. Cervical sympathetic blockade involves injecting a local anesthetic next to a group of nerves (ganglion) in the neck. The technique has been used clinically since 1925 with very few side effects. Finally, the neurobiology of SGB is discussed. Challenges to the use of SGB include the lack of randomized clinical trials and practitioners familiar with the use of SGB for PTSD.

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Year:  2015        PMID: 26073361     DOI: 10.1007/s11920-015-0599-4

Source DB:  PubMed          Journal:  Curr Psychiatry Rep        ISSN: 1523-3812            Impact factor:   5.285


  25 in total

1.  Stellate ganglion block for PTSD.

Authors:  Anita Hicky; Steven Hanling; Eric Pevney; Rhonda Allen; Robert N McLay
Journal:  Am J Psychiatry       Date:  2012-07       Impact factor: 18.112

Review 2.  Neuroimaging studies of emotional responses in PTSD.

Authors:  Israel Liberzon; Brian Martis
Journal:  Ann N Y Acad Sci       Date:  2006-07       Impact factor: 5.691

3.  Interventions for war-related posttraumatic stress disorder: meeting veterans where they are.

Authors:  Charles W Hoge
Journal:  JAMA       Date:  2011-08-03       Impact factor: 56.272

Review 4.  NGF regulatory role in stress and coping of rodents and humans.

Authors:  E Alleva; S Petruzzi; F Cirulli; L Aloe
Journal:  Pharmacol Biochem Behav       Date:  1996-05       Impact factor: 3.533

Review 5.  Role of norepinephrine in the pathophysiology and treatment of posttraumatic stress disorder.

Authors:  S M Southwick; J D Bremner; A Rasmusson; C A Morgan; A Arnsten; D S Charney
Journal:  Biol Psychiatry       Date:  1999-11-01       Impact factor: 13.382

6.  Effects of stellate ganglion block on sedation as assessed by bispectral index in normal healthy volunteers.

Authors:  Jinseok Yeo; Younghoon Jeon
Journal:  Pain Physician       Date:  2015 Mar-Apr       Impact factor: 4.965

Review 7.  Sympathetic nerve sprouting, electrical remodeling and the mechanisms of sudden cardiac death.

Authors:  P S Chen; L S Chen; J M Cao; B Sharifi; H S Karagueuzian; M C Fishbein
Journal:  Cardiovasc Res       Date:  2001-05       Impact factor: 10.787

8.  The role of NGF uptake in selective vulnerability to cell death in ageing sympathetic neurons.

Authors:  Kliment P Gatzinsky; Christopher Thrasivoulou; Maddalena Campioni-Noack; Clare Underwood; Tim Cowen
Journal:  Eur J Neurosci       Date:  2004-12       Impact factor: 3.386

Review 9.  Hippocampal vulnerability to stress and aging: possible role of neurotrophic factors.

Authors:  M A Smith
Journal:  Behav Brain Res       Date:  1996-06       Impact factor: 3.332

10.  Increased perivascular norepinephrine following intracerebroventricular infusion of NGF into adult rats.

Authors:  L G Isaacson; S C Billieu
Journal:  Exp Neurol       Date:  1996-05       Impact factor: 5.330

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  3 in total

Review 1.  Ganglion blocks as a treatment of pain: current perspectives.

Authors:  Osman Hakan Gunduz; Ozge Kenis-Coskun
Journal:  J Pain Res       Date:  2017-12-14       Impact factor: 3.133

2.  Efficacy and safety of stellate ganglion block in chronic ulcerative colitis.

Authors:  Hong-Ying Zhao; Guo-Tao Yang; Ning-Ning Sun; Yu Kong; Yun-Feng Liu
Journal:  World J Gastroenterol       Date:  2017-01-21       Impact factor: 5.742

3.  Stellate ganglion block treats posttraumatic stress: An example of precision mental health.

Authors:  James H Lynch
Journal:  Brain Behav       Date:  2020-08-28       Impact factor: 2.708

  3 in total

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